解放军医学院学报2025，Vol.46Issue(5)：425-428,441,5.DOI:10.12435/j.issn.2095-5227.24062101
基于解放军总医院某中心的小型猪动脉粥样硬化模型研究进展
Research advances in establishment and application of minipig atherosclerosis model
摘要
Abstract
Atherosclerosis(AS)is the main underlying pathology of ischemic coronary heart disease,stroke and peripheral macrovascular disease.The circulation system of pigs is similar to that of human,and AS can occur spontaneously with age,making it a good model for human AS research.This article combines the latest research on AS minipigs,as well as the research overview in the fields of AS vascular pathology research,intestinal flora research,inflammatory factor research,and metabolomics research.关键词
小型猪/动脉粥样硬化/动物模型/病理学/血管疾病Key words
minipig/atherosclerosis/animal model/pathology/vascular disease分类
医药卫生引用本文复制引用
陈华,赵玉琼,贾云晓,刘军,郭超..基于解放军总医院某中心的小型猪动脉粥样硬化模型研究进展[J].解放军医学院学报,2025,46(5):425-428,441,5.基金项目
国家自然科学基金项目(32370568) （32370568）
