北京中医药大学学报2025，Vol.48Issue(8)：1134-1139,6.DOI:10.3969/j.issn.1006-2157.2025.08.012
基于"滞伤脾胃"理论从"清浊归原"论治高尿酸血症
Treating hyperuricemia from"returning the clear and the turbid to the original"based on the theory of"indigestion of spleen and stomach"
摘要
Abstract
Hyperuricemia is a chronic metabolic disease resulting from purine metabolic dysfunction and is classified under the category of"blood turbidity"in traditional Chinese medicine.Our team termed it"acid turbidity,"and its pathogenesis is closely related to the dynamic evolution of the clear and the turbid components.With the change of modern people's diet structure,the incidence of hyperuricemia is increasing annually owing to the intake of fatty,sweet foods and alcohol.Therefore,this paper explores hyperuricemia from the"indigestion of spleen and stomach"theory.The core pathogenesis of hyperuricemia is indigestion of spleen and stomach,the inversion of clear and turbid substances,and endogenous acid turbidity.The initial manifestation of hyperuricemia is the internal retention of acid turbidity and ascending-descending disharmony;the gradual manifestation of this disease is that indigestion causes heat,and acid turbidity transforms into poison;the final manifestation of this disease is that secular indigestion causes deficiency and the inversion of clear and turbid substances.It can be summarized into three syndromes:syndromes of internal retention of dampness-turbidity,dampness-heat toxin amassment,and dampness-heat due to spleen deficiency.Therefore,this paper proposes to treat the disease according to different syndromes,with ascending the clear and descending the turbid as the core of treatment.And the therapeutic approach employs the flexible application of three methods:transportation,resolving,and transformation.For syndrome of internal retention of dampness-turbidity,treatment focuses on promoting spleen transportation to eliminate dampness;for syndrome of dampness-heat toxin amassment,the strategy is to resolve indigestion and purge heat;and for syndrome of dampness-heat due to spleen deficiency,the aim is to resolve turbidity and clear heat.By ascending the clear and descending the turbid,so that"returning the clear and the turbid to the original,"the spleen and stomach regain harmony,functions of ascending and descending are reestablished,and hyperuricemia can be effectively managed.关键词
高尿酸血症/滞伤脾胃/清浊归原/酸浊Key words
hyperuricemia/indigestion of spleen and stomach/returning the clear and the turbid to the original/acid turbidity分类
医药卫生引用本文复制引用
肇起巍,杨潇,刘昱灼,王梦真,罗玥,刘子玉,南明花,白长川,李欣宇,李佳..基于"滞伤脾胃"理论从"清浊归原"论治高尿酸血症[J].北京中医药大学学报,2025,48(8):1134-1139,6.基金项目
辽宁省自然科学基金面上项目(No.2024-MSLH-255) （No.2024-MSLH-255）
2024 年度中华中医药学会联合攻关项目(No.2024DYPLHGG-02) General Project of Natural Science Foundation of Liaoning Province(No.2024-MSLH-255) （No.2024DYPLHGG-02）
