川北医学院学报2025，Vol.40Issue(8)：997-1000,4.DOI:10.3969/j.issn.1005-3697.2025.08.008
血清CD71联合PCT水平对脓毒性休克患者短期预后的预测价值
The predictive value of CD71 and PCT for short-term prognosis in pa-tients with septic shock
摘要
Abstract
Objective:To explore the predictive value of transferrin receptor 1(CD71)and procalcitonin(PCT)in the short-term prognosis of patients with septic shock.Methods:150 patients with septic shock were selected as the research objects.According to the survival of patients 28 days after treatment,they were divided into survival group(n=89)and death group(n=61).Within 8 hours after admission,serum CD71,PCT and other laboratory indicators were measured in all patients.The differences were compared between the two groups of indicators.Logistic regression analysis was used to screen the influencing factors of prognosis,and the predic-tive value of each index for prognosis was evaluated by receiver operating characteristic curve(ROC).Results:A total of 150 cases were included,61 cases(40.67％,death group)died at 28 days,and 89 cases(59.33％,survival group)survived.Compared with the survival group,the patients in the death group had a greater age(P<0.05),a higher APACHE Ⅱ score(P<0.05),and serum PCT and CD71 levels were also increased(P<0.05).Multivariate Logistic regression analysis showed that APACHE Ⅱ score(OR=1.196),age(OR=1.068),PCT(OR=1.217)and CD71(OR=1.239)were independent factors affecting the short-term prognosis of patients with septic shock(P<0.05).Pearson correlation analysis showed that PCT(r=1.181)and CD71(r=0.236)were posi-tively correlated with APACHE Ⅱ score(P<0.05).ROC curve analysis showed that the area under the curve(AUC)of APACHE Ⅱ score,PCT and CD71 were 0.686,0.842 and 0.852,respectively.The AUC of PCT combined with CD71 was 0.930,the sensitivity and specificity were 86.89％and 89.89％,respectively.Conclusion:Both CD71 and PCT can be used to predict the short-term prognosis of patients with septic shock,and the predictive value of CD71 combined with PCT is higher than that of single application.关键词
脓毒性休克/转铁蛋白受体1/降钙素原/预后/联合预测Key words
Septic shock/Transferrin receptor 1/Procalcitonin/Prognosis/Joint prediction分类
医药卫生引用本文复制引用
赵婕,梁继芳,武卫东..血清CD71联合PCT水平对脓毒性休克患者短期预后的预测价值[J].川北医学院学报,2025,40(8):997-1000,4.基金项目
山西省科学技术厅基础研究计划项目(202403021212186) （202403021212186）
