肝胆胰外科杂志2025，Vol.37Issue(8)：524-528,封3,6.DOI:10.11952/j.issn.1007-1954.2025.08.004
LI-RADS中的CoE及EC征象诊断≤3.0cmHCC及预测MVI的价值
The value of corona enhancement and enhancing capsule features in LI-RADS for the diagnosis of HCC≤3.0 cm and the prediction of microvascular invasion
摘要
Abstract
Objective To analyze the diagnostic value of the liver imaging reporting and data system(LI-RADS)features——corona enhancement(CoE)and enhancing capsule(EC),in Gd-EOB-MRI examination for hepatocellular carcinoma(HCC)with a diameter≤3.0 cm.To explore the relationship between features of CoE,EC and microvascular invasion(MVI)and the corresponding predictive value for MVI.Methods A retrospective analysis was conducted on the medical records of 150 HCC patients,who underwent Gd-EOB-MRI at the First Affiliated Hospital of Zhejiang University(n=102)and Shulan(Hangzhou)Hospital(n=48)from Apr.2020 to Jul.2024.Chi-square test was used to compare the differences in imaging features between HCC and non-HCC lesions,as well as MVI-positive and MVI-negative lesions,to assess the diagnostic value of features CoE,EC,and CoE+EC for HCC.Multivariate Logistic regression analysis was performed to explore the relationship between CoE,EC,CoE+EC and MVI.Receiver operating characteristic(ROC)curves were plotted to evaluate the predictive value of CoE,EC,and CoE+EC for MVI.Results A total of 175 lesions were identified in 150 HCC patients.Statistically significant differences were found between HCC lesions and non-HCC lesions(n=31)in the terms of CoE,EC,and Co+EC(P<0.05).CoE,EC,and CoE+EC were significantly associated with MVI(P<0.001,P=0.009,P<0.001,respectively).The area under the ROC curve(AUC)of EC,CoE,and CoE+EC for predicting MVI were 0.68,0.70,and 0.71,respectively.Conclusion Imaging features CoE,EC,and CoE+EC all can enhance the diagnostic value of Gd-EOB-MRI for HCC with a diameter≤3.0 cm.The presence of CoE,EC,and CoE+EC can predict the existence of microvascular invasion(MVI)in HCC lesions,and the combination of CoE+EC has superior efficacy in predicting MVI.关键词
肝细胞癌/钆塞酸二钠增强磁共振/晕状强化/强化包膜/微血管侵犯Key words
hepatocellular carcinoma/Gd-EOB-MRI/corona enhancement/enhancing capsule/microvascular invasion分类
医药卫生引用本文复制引用
杨天,宋梦晨,叶圣利,曹国洪,陈峰..LI-RADS中的CoE及EC征象诊断≤3.0cmHCC及预测MVI的价值[J].肝胆胰外科杂志,2025,37(8):524-528,封3,6.基金项目
杭州市医药卫生科技项目(ZD20220053). （ZD20220053）
