广州医药2025，Vol.56Issue(7)：870-879,10.DOI:10.20223/j.cnki.1000-8535.2025.07.002
运动因子对心血管系统保护作用的研究进展
The protective effects of exerkines on cardiovascular system
摘要
Abstract
Exercise can prevent and treat cardiovascular diseases resulting from the metabolic disorders of glucose and lipid.Exerkines are defined as a series of bioactive substances in response to exercise including proteins,peptides,small molecular metabolites and nucleic acids.Multiple tissues can produce exerkines,such as skeletal muscle,adipose tissue,and liver.Many studies indicate that exerkines play essential roles in improving glucose and lipid metabolism,which are crucial to harness the health-related benefits mediated by exercise.In recent years,with the progression of proteomics,metabolomics and high-throughput sequencings,an increasing number of exerkines are discovered.These findings expand the research on beneficial effects of exercise and draw attention to the clinical implications of exerkines.This review aims to explore the influence of exerkines on cardiovascular system and reveal their potential roles in the prevention and treatment of cardiovascular disease.关键词
运动/运动因子/心血管疾病/代谢Key words
exercise/exerkines/cardiovascular disease/metabolism引用本文复制引用
欧阳嘉富,袁秋菊,江芷珊,范玉冰,冯彦翔,孙江鸥,刘东辉..运动因子对心血管系统保护作用的研究进展[J].广州医药,2025,56(7):870-879,10.基金项目
国家自然科学基金面上项目(32171174) （32171174）
