护理研究2025，Vol.39Issue(17)：2874-2880,7.DOI:10.12102/j.issn.1009-6493.2025.17.004
PICC导管相关性皮肤损伤病人生活质量的发展轨迹及其影响因素
Development trajectory of quality of life in patients with PICC-associated skin impairment and its influencing factors
摘要
Abstract
Objective:To explore the developmental trajectory of quality of life(QOL)in patients with peripherally inserted central catheter(PICC)-associated skin impairment(CASI)and to analyze its influencing factors.Methods:A total of 162 patients with PICC-related CASI from a tertiary tumor hospital in Fujian province were enrolled.General information questionnaires,the Contact Dermatitis Assessment Scale,and the Dermatology Life Quality Index(DLQI)were used for longitudinal assessments at three time points:at the onset of CASI(T1),one month post-onset(T2),and two months post-onset(T3).A latent class growth mixture model(GMM)and multinomial logistic regression were employed to analyze influencing factors.Results:The QOL scores of CASI patients at T1,T2,and T3 were(10.08±4.89),(12.65±4.33),and(15.09±6.19),respectively.The developmental trajectories of QOL were categorized into three groups:moderate impact-stable(50.6%),high impact-improving(7.4%),and moderate impact-worsening(42.0%).Regression analysis indicated that age,number of underlying diseases,delayed catheter maintenance,and contact dermatitis were significant influencing factors(P<0.05).Conclusions:The QOL of CASI patients exhibits heterogeneous developmental trajectories influenced by disease progression.Healthcare providers should develop targeted nursing interventions based on these factors to improve patients' QOL.关键词
导管相关性皮肤损伤/生活质量/经外周静脉置入中心静脉导管/发展轨迹/影响因素/潜变量增长混合模型Key words
catheter-associated skin impairment/quality of life/PICC/developmental trajectory/influencing factors/latent growth mixture model引用本文复制引用
齐榕,朱虹玉,柯熹,青菁,熊倩,骆惠玉..PICC导管相关性皮肤损伤病人生活质量的发展轨迹及其影响因素[J].护理研究,2025,39(17):2874-2880,7.基金项目
福建省自然科学基金项目,编号:2023J011241 （）
中华护理杂志社静脉治疗护理专项科研项目,编号:ZHHLZZS-202341 （）
