山西医科大学学报2025，Vol.56Issue(7)：805-810,6.DOI:10.13753/j.issn.1007-6611.2025.07.011
接骨续筋片质量标准提升研究
Quality standard improvement of Jiegu Xujin tablet
摘要
Abstract
Objective To improve the quality standard of Jiegu Xujin tablet.Methods The microscopic identification method was used to identify eremias,the thin-layer chromatography(TLC)method was used to identify Dioscoreae Nipponicae Rhizoma and Drynariae Rhizoma,and high performance liquid chromatography(HPLC)was established to determine the content of naringin in Rhi-zoma Drynariae.Results The microscopic identification for eremias was strongly specific with good detection probability.The TLC for Dioscoreae Nipponicae Rhizoma and Drynariae Rhizoma showed clear spots and strong specificity with good durability.The linear range of naringin was 0.038 3-4.787 1 μg,and the regression equation was y=1 723 987.21x-4 337.64(R2=1.00).The average reco-very was 102.2％(n=9)with RSD of 1.5％.The RSDs of precision,stability and repeatability were all less than 0.5％.Conclusion The newly established microscopic identification,TLC and HPLC are accurate and reliable with simple operation and good reprodu-cibility,and can be used for the quality evaluation,which provides scientific basis for the quality control of Jiegu Xujin tablet.关键词
接骨续筋片/标准提升/薄层色谱/高效液相色谱Key words
Jiegu Xujin tablet/standard improvement/thin-layer chromatography/high performance liquid chromatography分类
医药卫生引用本文复制引用
杨艳,杨立,郝云芳,张峰..接骨续筋片质量标准提升研究[J].山西医科大学学报,2025,56(7):805-810,6.基金项目
国家药典委员会药品标准提高项目(443) （443）
