应用化学2025，Vol.42Issue(8)：1035-1056,22.DOI:10.19894/j.issn.1000-0518.250087
聚集诱导发光型荧光探针在生物标志物检测中的研究进展
Research Progress of Fluorescent Probes Based on Aggregation-Induced Emission for Detection of Biomarkers
黄欣欣 1石有圣 2邓涛 3蔡春1
作者信息
- 1. 南京理工大学化学与化工学院,南京 210094
- 2. 聊城市科技信息研究中心,聊城 252000
- 3. 佛山大学医学院,佛山 528000
- 折叠
摘要
Abstract
Aggregation-induced emission(AIE)has received increasing attention and has been applied widely in various fields such as biochemical analysis and optoelectronic materials.Unlike conventional fluorescent probes,AIE fluorescent probes exhibit strong luminescence due to limited intramolecular movement caused by steric hindrance after aggregation.AIE fluorescent probes reveal higher selectivity,sensitivity,signal-to-noise ratio,and shorter response time.These advantages make AIE a promising tool in biochemical detection,early diagnosis and treatment of disease and cell imaging.Herein,the applications of AIE fluorescent probes in the detection of different biomarkers are summarized.In addition,challenges and development prospects of AIE fluorescent probes in the future are discussed.关键词
聚集诱导发光/荧光探针/生物标志物/生物成像Key words
Aggregation-induced emission/Fluorescent probes/Biomarkers/Biological imaging分类
化学化工引用本文复制引用
黄欣欣,石有圣,邓涛,蔡春..聚集诱导发光型荧光探针在生物标志物检测中的研究进展[J].应用化学,2025,42(8):1035-1056,22.
