组织工程与重建外科杂志2025，Vol.21Issue(4)：396-400,5.DOI:10.3969/j.issn.1673-0364.2025.04.011
胸腺上皮细胞在免疫调节中的作用
The role of thymic epithelial cells in immune regulation
摘要
Abstract
The thymus is an important central immune organ that provides the microenvironment necessary for the development of T lymphocytes from hematopoietic stem cells.Thymic epithelial cells(TECs),as one of the most critical components of the thymic microenvironment,play an important role in immune regulation.Thymic epithelial cells are mainly categorized into cortical epithelial cells and medullary epithelial cells,which mediate the positive and negative selection of thymocytes,respectively.From the perspective of the pathway of action,thymic epithelial cells mainly regulate thymocyte development through the secretion of cytokines,thymic hormones,or direct interaction with thymocytes.In this paper,the role of thymic epithelial cells in immunomodulation was reviewed.关键词
胸腺上皮细胞/T淋巴细胞/免疫调节Key words
Thymic epithelial cells/T lymphocytes/Immunomodulation分类
医药卫生引用本文复制引用
何敏燕,刘菲,杨军,周显玉..胸腺上皮细胞在免疫调节中的作用[J].组织工程与重建外科杂志,2025,21(4):396-400,5.基金项目
国家自然科学基金青年项目(82102354). （82102354）
