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Rapid access to diverse indoles by addition/S_(N)Ar with Grignard reagents and 2-fluorophenyl acetonitriles

Yuanyun Gu Yaxin Feng Baotong Huang Yan-En Wang Yaqi Yuan Dan Xiong Yonghong Hu Xiufang Xu Patrick J.Walsh Jianyou Mao

Green Synthesis and Catalysis2025，Vol.6Issue(2)：P.171-178,8.

Green Synthesis and Catalysis2025，Vol.6Issue(2)：P.171-178,8.DOI:10.1016/j.gresc.2024.02.004

Rapid access to diverse indoles by addition/S_(N)Ar with Grignard reagents and 2-fluorophenyl acetonitriles

Yuanyun Gu ¹Yaxin Feng ²Baotong Huang ²Yan-En Wang ³Yaqi Yuan ¹Dan Xiong ¹Yonghong Hu ⁴Xiufang Xu ²Patrick J.Walsh ⁵Jianyou Mao¹

作者信息

1. Technical Institute of Fluorochemistry(TIF),State Key Laboratory of Materials Oriented Chemical Engineering(MCE),School of Chemistry and Molecular Engineering,Nanjing Tech University,30 South Puzhu Road,Nanjing 211816,China
2. Department of Chemistry,Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education),College of Chemistry,Nankai University,Tianjin 300071,China
3. College of Science,Hebei Agricultural University,Baoding 071000,China
4. College of Food Science and Light Industry,Nanjing Tech University,Nanjing 211800,China
5. Roy and Diana Vagelos Laboratories,Department of Chemistry,University of Pennsylvania,Philadelphia 19104-6323,USA
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摘要

关键词

2-Aryl indoles/Grignard reagents/2-Fluorobenzyl cyanides/S_(N)Ar/Indomethacin

分类

化学化工

引用本文复制引用

Yuanyun Gu,Yaxin Feng,Baotong Huang,Yan-En Wang,Yaqi Yuan,Dan Xiong,Yonghong Hu,Xiufang Xu,Patrick J.Walsh,Jianyou Mao..Rapid access to diverse indoles by addition/S_(N)Ar with Grignard reagents and 2-fluorophenyl acetonitriles[J].Green Synthesis and Catalysis,2025,6(2):P.171-178,8.

基金项目

the National Natural Science Foundation of China(No.22071107) （No.22071107）

the Natural Science Foundation of Jiangsu Province,China(No.BK20211588) （No.BK20211588）

Provincial Key Research and Development Program of Jiangsu(Modern Agriculture)(No.BE2023333) （Modern Agriculture）

The Natural Science Foundation of Hebei Province(C2023204011) （C2023204011）

PJW acknowledges the US NSF(No.CHE-2154593). （No.CHE-2154593）

Green Synthesis and Catalysis

ISSN：2666-5549

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