中国当代医药2025，Vol.32Issue(23)：16-20,26,6.DOI:10.3969/j.issn.1674-4721.2025.23.03
基于焦虑-抑郁-社会支持特征的妊娠糖尿病患者亚组低血糖风险及影响因素
Hypoglycemia risk and influencing factors in the subgroup of patients with gestational diabetes mellitus based on anxiety-depression-social sup-port characteristics
摘要
Abstract
Objective To conduct a latent profile analysis(LPA)of patients with gestational diabetes mellitus(GDM)based on the anxiety-depression-social support characteristics,and identify subgroups of hypoglycemia risk and influencing factors.Methods A total of 279 patients with GDM who visited Zhuhai Center for Maternal and Child Health Care from October 2022 to February 2023 were selected as the research subjects.Their psychosocial characteristics were evaluated using the self-rating anxiety scale,the Edinburgh postnatal depression scale,and the social support rating scale.Subgroups were divided by LPA,and combined with the occurrence of hypoglycemia,multivariate logistic regression analysis was used to analyze the influencing factors of hypoglycemia.Results Two subgroups,namely group C1(low de-pression-low anxiety-high support group)and group C2(high anxiety-high depression-low support group)were delineated by LPA.The incidence of hypoglycemia in group C2 was higher than that in group C1,the difference was sta-tistically significant(P＜0.05).The results of univariate analysis showed that the mode of conception,the number of fetuses,the frequency of blood glucose monitoring,no snack 1-2 hours before bedtime,insufficient weekly weight gain and subgroup classification were all related to the occurrence of hypoglycemia(P＜0.05).The results of multivariate logistic regression analysis showed that subgroup C2(β=0.983,OR=2.673,95％CI:1.127-6.339)and non-self-monitored blood glucose(β=1.031,OR=2.803,95％CI:1.118-7.030)were independent risk factors for hy-poglycemia(P＜0.05),and natural conception([3=-0.965,OR=0.381,95％CI:0.158-0.922)was an independent protective factor(P＜0.05).Conclusion The LPA model based on the anxiety-depression-social support characteristics can accurately identify the high-risk subgroup(group C2)of hypoglycemia in patients with GDM.Clinically,targeted psychological intervention and blood glucose management need to be strengthened,and the protective role of embryo transfer conception and regular blood glucose monitoring should be emphasized to optimize the prevention and control strategy of hypoglycemia.关键词
妊娠糖尿病/焦虑/抑郁/社会支持/低血糖/影响因素/潜在剖面分析Key words
Gestational diabetes mellitus/Anxiety/Depression/Social support/Hypoglycemia/Influencing factors/Latent profile analysis分类
医药卫生引用本文复制引用
杨洁梅,贝雪娜,郭彬彬,彭融融,王利枝,刘彩霞..基于焦虑-抑郁-社会支持特征的妊娠糖尿病患者亚组低血糖风险及影响因素[J].中国当代医药,2025,32(23):16-20,26,6.基金项目
广东省珠海市社会发展领域科技计划项目(一般项目)(2220004000318). （一般项目）
