临床眼科杂志2025，Vol.33Issue(4)：300-304,5.DOI:10.3969/j.issn.1006-8422.2025.04.003
577nm阈下微脉冲激光对黄斑中心凹500μm之内急性CSC患者黄斑区结构及微循环的影响
Effects of 577 nm subthreshold micropulse laser on macular structure and microcirculation in patients with acute central serous chorioretinopathy
沈雨凡 1李喆1
作者信息
- 1. 225001 江苏扬州,江苏省苏北人民医院眼科
- 折叠
摘要
Abstract
Objective To observe the changes of macular structure and microcirculation in patients with acute central serous chorioretinopathy(CSC)after 577 nm subthreshold micropulse laser(SML)treatment.Methods Retro-spective case study.Included 36 patients(36 eyes)diagnosed with acute CSC and leakage point within 500 μm of the macular fovea in the Su Bei Hospital from August 2022 to October 2023.Results(1)Best corrected visual acuity(BCVA)in acute CSC patients was significantly higher at 3 months following treatment than before the treatment(P<0.05).(2)Central macular thickness(CMT)was significantly lower at 1 month and 3 months following therapy compared to before the treatment(all P<0.05).The subfoveal choroidal thickness(SFCT)at 1 and 3 months following SML treatment was lower than that before the treatment,and the difference was found to be statistically significant(all P<0.05).Chorio-capillaris vessel density(CCVD)increased significantly at 3 months following treatment compared to at 1 month following treatment(P<0.05).At 3 months after SML therapy,foveal superficial capillary plexus vessel density(SCPVD)and fo-veal deep capillary plexus vessel density(DCPVD)were significantly decreased compared with those before the treatment(all P<0.05).(3)The vessel density around the foveal avascular zone 300 μm wide ring(FD-300)was significantly higher at 1 month and 3 months following therapy than before the treatment(all P<0.05).Conclusions For patients with acute CSC with the leakage point located within 500 μm of the macular fovea,577 nm-SML treatment can quickly reduce the CMT and SFCT,and gradually increase the CCVD,reduce the SCPVD and DCPVD.关键词
急性中心性浆液性脉络膜视网膜病变/577nm阈下微脉冲激光/相干光层析血管成像术/黄斑区形态/血流密度Key words
Acute central serous chorioretinopathy/577 nm subthreshold micropulse laser/Optical coherence to-mography angiography/Morphology of macular area/Vessel density引用本文复制引用
沈雨凡,李喆..577nm阈下微脉冲激光对黄斑中心凹500μm之内急性CSC患者黄斑区结构及微循环的影响[J].临床眼科杂志,2025,33(4):300-304,5.
