临床眼科杂志2025，Vol.33Issue(4)：372-377,6.DOI:10.3969/j.issn.1006-8422.2025.04.017
难治性糖尿病性黄斑水肿的视网膜因素
Retinal factors in refractory diabetic macular edema
杨雅楠 1王鲜 2王芬 1朱同乐3
作者信息
- 1. 550004 贵阳,贵州医科大学||556000 凯里,贵州医科大学第二附属医院眼科
- 2. 550004 贵阳,贵州医科大学||550004 贵阳,贵州医科大学附属医院眼科
- 3. 556000 凯里,贵州医科大学第二附属医院眼科
- 折叠
摘要
Abstract
Diabetic macular edema(DME)is the most common cause of vision loss in diabetes mellitus(DM)eyes,and as the number of DM patients rapidly increases,so does the number of patients with DME.The emergence of anti-vascular endothelial growth factor(VEGF)drugs has replaced laser photocoagulation as the first-line treatment for DME,bringing improvement to many patients,but refractory DME remains a challenge due to the extremely complex pathogenesis of DME and the involvement of many different biochemical pathways.This review analyzes the retinal factors associated with the formation of refractory DME,briefly describes the physiological role of Müller cells and damage forma-tion,and briefly analyzes the possible mechanisms of vitreoretinal pulling,central concave structures,microaneurysms,and the formation of several OCT markers,as well as their impact on the response to DME treatment.关键词
难治性糖尿病性黄斑水肿/Müller细胞/微动脉瘤/视网膜因素Key words
Refractory diabetic macular edema/Müller cell/Microaneurysms/Retinal factors引用本文复制引用
杨雅楠,王鲜,王芬,朱同乐..难治性糖尿病性黄斑水肿的视网膜因素[J].临床眼科杂志,2025,33(4):372-377,6.
