武警医学2025，Vol.36Issue(8)：664-667,4.
北京某三甲医院2021-2023年眼部感染患者病原菌分布状况及其耐药性分析
Analysis of the distribution of pathogenic bacteria and drug resistance in patients with ocular infection in a tertiary hospital in Beijing from 2021 to 2023
刘佳 1王玉飞 1孙涛 1曹雪平 1张金红 1张薇1
作者信息
- 1. 100039 北京,解放军总医院第三医学中心检验科
- 折叠
摘要
Abstract
Objective To analyze the distribution of pathogenic bacteria and their drug resistance in patients with ocular in-fection in a tertiary hospital in Beijing,and to provide reference for the clinical rational use of antibiotics.Methods A retrospective analysis was conducted to statistically analyze the composition and drug resistance of specimens submitted by patients with ocular in-fection in a tertiary hospital in Beijing from January 2021 to December 2023.Results A total of 255 pathogenic strains were iso-lated,with a positive rate of 56.42％.Among them,134(52.55％)strains of Gram-positive bacilli,71(27.84％)strains of Gram-negative bacilli,39(15.29％)strains of Gram-positive bacilli,and 11(4.31％)strains of fungi were detected.The top 5 patho-genic bacteria isolations were Staphylococcus aureus,Staphylococcus epidermidis,Corynebacterium,Pseudomonas aeruginosa,and Streptococcus viridans,accounting for 18.04％,14.09％,10.20％,7.45％,and 7.06％,respectively.The results of drug suscep-tibility tests showed that Gram-positive cocci had the highest resistance rate to penicillin and erythromycin,and the lowest resistance rate to vancomycin and linezolid.Enterobacteriaceae had lower resistance rate to levofloxacin and ciprofloxacin,at 28.00％and 24.00％,respectively.The overall resistance rate of Pseudomonas aeruginosa was relatively low.Conclusions The isolated bacte-ria from patients with ocular infection are mainly staphylococci,with Staphylococcus aureus being the most common one.Gram-posi-tive bacteria are generally resistant to penicillin and erythromycin,but have lower resistance rate to rifampicin,and can be a better choice in clinically practice.The resistance rate of Gram-negative bacteria is generally low,and quinolones and aminoglycosides can be a choice in empirical practice.关键词
眼部感染/病原菌/药敏试验/耐药性Key words
ocular infection/pathogenic bacteria/drug susceptible test/drug resistance分类
医药卫生引用本文复制引用
刘佳,王玉飞,孙涛,曹雪平,张金红,张薇..北京某三甲医院2021-2023年眼部感染患者病原菌分布状况及其耐药性分析[J].武警医学,2025,36(8):664-667,4.
