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The arginine metabolism battlefield:how metabolite exchange in the tumor microenvironment shapes an immunosuppressive ecosystem

Yinghua Zhu Hongde Li Hongbo Hu Hai Hu Man-Li Luo

癌症生物学与医学（英文版）2025，Vol.22Issue(8)：874-880,7.

癌症生物学与医学（英文版）2025，Vol.22Issue(8)：874-880,7.DOI:10.20892/j.issn.2095-3941.2025.0202

The arginine metabolism battlefield:how metabolite exchange in the tumor microenvironment shapes an immunosuppressive ecosystem

Yinghua Zhu ¹Hongde Li ²Hongbo Hu ³Hai Hu ⁴Man-Li Luo⁵

作者信息

1. Department of Biochemistry and Molecular Biology,School of Basic Medical Sciences,Southern Medical University,Guangzhou 510515,China
2. Hangzhou Institute of Medicine,Chinese Academy of Sciences,Zhejiang Cancer Hospital,Hangzhou 310018,China
3. Center for Immunology and Hematology,Department of Biotherapy and Cancer Center,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu 610211,China
4. Breast Cancer Center,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine,Chinese Academy of Sciences,Hangzhou 310022,China
5. Medical Research Center,Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangzhou 510120,China||Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation,Guangdong-Hong Kong Joint Laboratory for RNA Medicine,Sun Yat-Sen Memorial Hospital,Sun Yat-Sen University,Guangzhou 510120,China
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摘要

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Yinghua Zhu,Hongde Li,Hongbo Hu,Hai Hu,Man-Li Luo..The arginine metabolism battlefield:how metabolite exchange in the tumor microenvironment shapes an immunosuppressive ecosystem[J].癌症生物学与医学（英文版）,2025,22(8):874-880,7.

基金项目

This work was supported by grants from the National Key R&D Program of China(Grant no.2022YFC3401001),the National Natural Science Foundation of China(Grant nos.82025026,82230091,and 81872144),and the Guangdong Basic and Applied Basic Research Foundation(Grant no.2023A1515140033). （Grant no.2022YFC3401001）

癌症生物学与医学（英文版）

ISSN：2095-3941

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