首页|期刊导航|癌症生物学与医学（英文版）|Proteomic profiling and scRNA sequencing identify signatures associated with Helicobacter pylori infection and risk of developing gastric cancer

Proteomic profiling and scRNA sequencing identify signatures associated with Helicobacter pylori infection and risk of developing gastric cancer

Yu Jin Wenqing Li Xue Li Bingyao Cai Lanxin Yang Wenjing Zhao Hengmin Xu Yang Zhang Zongchao Liu Kaifeng Pan

癌症生物学与医学（英文版）2025，Vol.22Issue(8)：946-963,18.

癌症生物学与医学（英文版）2025，Vol.22Issue(8)：946-963,18.DOI:10.20892/j.issn.2095-3941.2025.0077

Proteomic profiling and scRNA sequencing identify signatures associated with Helicobacter pylori infection and risk of developing gastric cancer

Yu Jin ¹Wenqing Li ¹Xue Li ²Bingyao Cai ³Lanxin Yang ¹Wenjing Zhao ¹Hengmin Xu ¹Yang Zhang ⁴Zongchao Liu ¹Kaifeng Pan¹

作者信息

1. State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,Peking University Cancer Hospital&Institute,Beijing 100142,China
2. Department of Cancer Prevention,Zhejiang Cancer Hospital,Hangzhou Institute of Medicine(HIM),Chinese Academy of Sciences,Hangzhou 310022,China
3. School of Public Health,Peking University,Beijing 100191,China
4. Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education),Peking University Cancer Hospital&Institute,Beijing 100142,China
折叠

摘要

关键词

Stomach neoplasms/Helicobacter pylori/proteomics/scRNA-seq/biomarker

Key words

Stomach neoplasms/Helicobacter pylori/proteomics/scRNA-seq/biomarker

引用本文复制引用

Yu Jin,Wenqing Li,Xue Li,Bingyao Cai,Lanxin Yang,Wenjing Zhao,Hengmin Xu,Yang Zhang,Zongchao Liu,Kaifeng Pan..Proteomic profiling and scRNA sequencing identify signatures associated with Helicobacter pylori infection and risk of developing gastric cancer[J].癌症生物学与医学（英文版）,2025,22(8):946-963,18.

基金项目

We are indebted and thankful to all participants for their val-uable contributions.The authors would also like to thank the GEO database and UK Biobank Pharma Proteomics Project(UKB-PPP)consortium for providing their platforms and contributors for their meaningful datasets.This research was conducted using the UK Biobank Resource under Application No.90999.This study was funded by the National Natural Science Foundation of China(Grant No.82273704),Noncommunicable Chronic Diseases-National Science and Technology Major Project(Grant Nos.2023ZD0501400-2023ZD0501402),Beijing Hospitals Authority's Ascent Plan(Grant No.DFL20241102),Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support(Grant No.ZLRK202325),Peking University Medicine Fund for World's Leading Discipline or Discipline Cluster Development(Grant No.BMU2022XKQ004),and the Science Foundation of Peking University Cancer Hospital(Grant Nos.BJCH2024BJ02,XKFZ2410,and 2022-27). （UKB-PPP）

癌症生物学与医学（英文版）

ISSN：2095-3941

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