长春中医药大学学报2025，Vol.41Issue(9)：963-965,3.DOI:10.13463/j.cnki.cczyy.2025.09.005
重构本草——虎杖
Reconstruction of Chinese materia medica-giant knotweed rhizome
摘要
Abstract
Through investigation of ancient books and the sorting of modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of famous experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that giant knotweed rhizome mainly has the effects of promoting diuresis and eliminating jaundice,clearing heat and detoxifying,and dispersing blood stasis and relieving pain.The symptom targets are jaundice,joint swelling and pain,and frequent urination and urgency.The biochemical indicator targets are high bilirubin,elevated liver enzymes,and fatty liver.Modern pharmacological studies have found that giant knotweed rhizome and its active ingredients have effects of promoting bile secretion and eliminating jaundice,anti-inflammation and analgesia,diuresis,liver protection and enzyme reduction,and improving fatty degeneration of liver cells.This product contains anthraquinone components,which is somewhat toxic and has a bitter-cold property.It is not suitable for long-term use and is contraindicated for pregnant women.The commonly used clinical dosage is 9-40 g.关键词
虎杖/症靶/标靶/重构本草/临床回归Key words
giant knotweed rhizome/symptom target/biochemical indicator target/reconstruction of Chinese materia medica/clinical verification分类
医药卫生引用本文复制引用
张蓝月,吴学敏,钟小美,何莉莎..重构本草——虎杖[J].长春中医药大学学报,2025,41(9):963-965,3.基金项目
国家自然基金委-中国科学院联合项目资助中西医结合创新范式战略研究(XK2023SMC003) （XK2023SMC003）
成都市卫生健康委员会成都中医药大学2024年度委校联合创新基金联合创新项目(WXLH202403050) （WXLH202403050）
广东省深圳市"医疗卫生三名工程"仝小林院士中医代谢病团队项目(SZZYSM20220210) （SZZYSM20220210）
2024年广州中医药大学深圳医院<福田>科研专项(GZYSY2024043) （GZYSY2024043）
