南方医科大学学报2025，Vol.45Issue(9)：2046-2054,9.DOI:10.12122/j.issn.1673-4254.2025.09.24
细胞外囊泡在神经系统疾病中的治疗潜力
Therapeutic potential of extracellular vesicles in neurological diseases
摘要
Abstract
Extracellular vesicles(EVs),nanoscale lipid bilayer vesicles actively secreted by organisms into the extracellular environment,are rich in specific bioactive substances,such as proteins,genetic materials and lipids.These vesicles are involved in intercellular interactions and can pass through the blood-brain barrier,and may thus potentially serve as important biological substances for treatment of neurological diseases.In this review,we summarize the biological origin of EVs and their therapeutic potential in neurological diseases,expound the possibility of EV-based treatment of neurological diseases using traditional Chinese medicine,and discuss the challenges and prospects of researches of EVs for the treating neurological diseases.关键词
细胞外囊泡/神经系统疾病/治疗/载药疗法Key words
extracellular vesicles/neurological disorders/treatment/medicated therapy引用本文复制引用
杜庆锋,杨超,夏雪晴,王婷..细胞外囊泡在神经系统疾病中的治疗潜力[J].南方医科大学学报,2025,45(9):2046-2054,9.基金项目
国家高水平中医药重点学科建设项目(ZYYZDXK-2023152) （ZYYZDXK-2023152）
广东省医学科学技术研究基金项目(A2024076) （A2024076）
