动物医学进展2025，Vol.46Issue(10)：126-131,6.
革兰氏阳性菌外囊泡在宿主细胞炎症中的促炎和抗炎作用
The Dual Role of Gram-positive Extracellular Vesicles in Host Cell Inflammation
摘要
Abstract
Extracellular vesicles(EVs),as important mediators of communication between bacteria and host cells,play a key role in regulating host immune responses by delivering bioactive molecules.Currently,more studies have been conducted on EVs from Gram-negative bacteria and eukaryotic cells,with a more in-depth understanding of their structures,compositions and functions,whereas the mechanisms of host-host interactions of Gram-positive bacterial EVs and their immunomodulatory roles are still relatively un-derstudied.This paper reviews the biogenesis of Gram-positive bacterial EVs and the key bacterial compo-nents they carry,and provides insights into their dual role in the host's cellular inflammatory response.It provides not only a new theoretical perspective for elucidating microbe-host interactions,but also an impor-tant theoretical basis for the development of EV-based therapeutic strategies for inflammatory diseases.关键词
细菌/外囊泡/促炎反应/抗炎反应Key words
Bacteria/Exovesicular/Proinflammatory response/Anti-inflammatory response分类
农业科技引用本文复制引用
黄倩,杨文琳,李军..革兰氏阳性菌外囊泡在宿主细胞炎症中的促炎和抗炎作用[J].动物医学进展,2025,46(10):126-131,6.基金项目
宁夏回族自治区自然科学基金项目"携带PV-杀白细胞素金黄色葡萄球菌膜囊泡引起的奶牛乳腺上皮细胞炎症和凋亡机制研究"(2023AAC03322) （2023AAC03322）
2023年宁夏回族自治区青年拔尖人才培养项目(宁人社函[2024]106号) （宁人社函[2024]106号）
