南方医科大学学报2025，Vol.45Issue(9)：1880-1888,9.DOI:10.12122/j.issn.1673-4254.2025.09.08
术中肾脏集合系统受损是肾部分切除术后同侧上尿路结石发病的危险因素:一项1∶2匹配病例对照研究
Intraoperative renal collecting system damage increases risks of ipsilateral upper urinary tract stones after partial nephrectomy:a 1∶2 propensity-matched case-control study
摘要
Abstract
Objective To investigate the incidence of ipsilateral upper urinary tract stones after partial nephrectomy and its risk factors.Methods We retrospectively analyzed baseline patient characteristics(age,gender,and body mass index),smoking,alcohol consumption,comorbidities(hypertension,diabetes,hypertriglyceridemia,hyperuricemia,and cardiovascular diseases),preoperative tumor conditions(tumor diameter,multiple foci,location,hemorrhage,necrosis,cystic changes,and endophytic growth),preoperative glomerular filtration rate and intraoperative factors(renal collecting system damage,ischemia time,operation time,surgical approach,and estimated intraoperative blood loss)to identify the risk factors for ipsilateral upper urinary tract stones following partial nephrectomy in our center.Results The overall incidence of upper urinary tract stones following partial nephrectomy was 7.80%(112/1435).The incidence of ipsilateral upper urinary tract stones was significantly higher than those of contralateral stones(4.95%vs 1.46%,P<0.001)and bilateral stones(4.95%vs 1.39%,P<0.001).Intraoperative damage to the renal collecting system was identified as a significant risk factor for ipsilateral upper urinary tract stones(OR=4.550,95%CI:2.237-9.252,P<0.001).Diabetes was a probable risk factor for secondary ipsilateral upper urinary tract stones after partial nephrectomy(OR=2.419,95%CI:0.973-6.012,P=0.057).Conclusions The incidence of ipsilateral upper urinary tract stones after partial nephrectomy is higher than that of contralateral and bilateral stones.Intraoperative renal collecting system damage is a risk factor for secondary ipsilateral upper urinary tract stones after partial nephrectomy.关键词
肾部分切除术/尿石症/肾脏集合系统Key words
partial nephrectomy/urolithiasis/renal collecting system引用本文复制引用
刘炎忠,朱润,李玉柱,马鑫,麦海星..术中肾脏集合系统受损是肾部分切除术后同侧上尿路结石发病的危险因素:一项1∶2匹配病例对照研究[J].南方医科大学学报,2025,45(9):1880-1888,9.基金项目
解放军总医院青年自主创新科学基金(22QNFC045) （22QNFC045）
中国人民解放军总医院第三医学中心学科创新发展专项(2024BJ-13) （2024BJ-13）
