影像科学与光化学2025，Vol.43Issue(6)：77-83,7.DOI:10.7517/issn.1674-0475.2025.06.11
多模态磁共振成像对非狭窄性颅内动脉粥样硬化斑块所致缺血性脑卒中风险的评估
Multimodal Magnetic Resonance Imaging in Assessing the Risk of Ischemic Stroke Caused by Non Stenotic Intracranial Atherosclerotic Plaque
摘要
Abstract
Objective:To explore the value of multimodal magnetic resonance imaging(MRI)in assessing the risk of ischemic stroke(IS)caused by non stenotic intracranial atherosclerotic plaque.Methods:The data of 178 patients with non-stenosis intracranial atherosclerotic plaques diagnosed from January 2021 to December 2023 were collected.Ingenia 3.0T CX MRI was used for multimodal imaging,including three-dimensional time-of-flight MRI,DWI,T2WI,T1WI scan,and then high-resolution MRI examination,T1WI scan,T2WI scan,and T1WI enhanced scan.According to whether IS occurred within 12 months of diagnosis,it was divided into the occurrence group(n=60)and the non-occurrence group(n=118).The basic data of patients and multimodal MRI parameters were statistically analyzed,and their evaluation value for IS risk was analyzed.Results:The plaque volume of the occurrence group was larger than that of the non-occurrence group,(50.03±10.72)mm3 and(36.89±11.05)mm3,respectively(P<0.001).The plaque enhancement rate of the occurrence group was larger than that of the non-occurrence group,(63.87%±6.55%)and(56.23%±5.13%),respectively(P<0.001).The area of the narrowest lumen in the occurrence group was smaller than that in the non-occurrence group,(3.58±0.58)mm2 and(4.73±0.63)mm2,respectively(P<0.001).The area under the receiver operating characteristic curve(AUC)of the prediction model based on plaque volume,plaque enhancement rate and the narrowest lumen area was 0.970,the sensitivity was 96.7%,and the specificity was 86.4%,indicating that the model had good predictive value.Conclusion:Multimodal MRI has certain evaluation value for the risk of IS caused by non-stenosis intracranial atherosclerotic plaques.Based on the risk prediction model constructed by the main parameters,the contribution of each factor to the risk of IS is intuitively expressed through the nomogram,which provides a quantitative evaluation tool for clinical practice.关键词
脑卒中/非狭窄性颅内动脉粥样硬化/斑块/多模态磁共振成像Key words
stroke/non-stenosis intracranial atherosclerosis/plaques/multimodal magnetic resonance imaging分类
医药卫生引用本文复制引用
朱秀芳,陈磊,段新秀,李蕾..多模态磁共振成像对非狭窄性颅内动脉粥样硬化斑块所致缺血性脑卒中风险的评估[J].影像科学与光化学,2025,43(6):77-83,7.基金项目
连云港市科技项目(SF2315). （SF2315）
