国际老年医学杂志2025,Vol.46Issue(5):513-517,5.DOI:10.3969/j.issn.1674-7593.2025.05.001
慢性炎症与衰弱的研究进展
Research advances in chronic inflammation and frailty
摘要
Abstract
Chronic inflammation and frailty have emerged as key focal points in the field of geriatric medicine.This review summarizes the research progress on chronic inflammation and frailty,encompassing definitions and assessment methods of frailty,mechanistic discussions on their interplay,and advances in key inflammatory biomarkers such as C-reactive protein,interleukin-6,tumor necrosis factor-alpha,and biomarker panels.The review aims to provide a theoretical foundation for establishing prevention and intervention systems targeting frailty through inflammation-modulating strategies,and it has important clinical guiding significance for improving the health prognosis of the elderly.关键词
慢性炎症/衰弱/C反应蛋白/白细胞介素-6/肿瘤坏死因子-α/生物标志物组合Key words
Chronic inflammation/Frailty/C-reactive protein/Interleukin-6/Tumor necrosis factor-α/Biomarker panel引用本文复制引用
邓瑞冰,王晓明,张伟,靳英,贾新..慢性炎症与衰弱的研究进展[J].国际老年医学杂志,2025,46(5):513-517,5.基金项目
陕西省重点研发计划项目(2024SF-ZDCYL-01-12) (2024SF-ZDCYL-01-12)