实用临床医药杂志2025，Vol.29Issue(15)：1-5,5.DOI:10.7619/jcmp.20245703
多模态超声联合免疫炎症指标预测乳腺癌腋窝淋巴结转移的价值
Value of multimodal ultrasound combined with immune-inflammatory indicators in predicting axillary lymph node metastasis in patients with breast cancer
摘要
Abstract
Objective To investigate the value of multimodal ultrasound combined with immune-inflammatory indicators in predicting axillary lymph node(ALN)metastasis in patients with breast cancer.Methods The clinical data of 106 breast cancer patients treated in the Ultrasound Depart-ment of Nantong Cancer Hospital from January 2023 to June 2024 were analyzed,and the patients were divided into ALN metastasis group and non-metastasis group based on postoperative pathological re-sults.Univariate and multivariate Logistic regression models were used to analyze the immune-inflam-matory indicators and ultrasound parameters in both groups.The receiver operating characteristic(ROC)curve was plotted to evaluate the predictive value of each indicator.Results Univariate anal-ysis showed significant differences between the ALN metastasis group and the non-metastasis group in terms of the neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),aspect ratio,maximum tumor diameter,and Adler blood flow grade(P＜0.05).NLR,PLR,maximum tumor di-ameter,and Adler blood flow grade were independent influencing factors for predicting ALN metastasis in breast cancer(P＜0.05).The area under the curve(AUC)for predicting ALN metastasis using multimodal ultrasound combined with immune-inflammatory indicators was 0.877,with a diagnostic sensitivity of 84.7％and a specificity of 76.6％.The predictive efficacy of the combined multi-indicators was significantly higher than that of individual indicators(P＜0.05).Conclusion Multimodal ultrasound combined with immune-inflammatory indicators is associated with ALN metastasis in breast cancer patients and can provide a reference basis for clinical diagnosis,subsequent treatment,and prognosis evaluation.关键词
多模态超声/炎症指标/乳腺癌/淋巴结转移/预测效能/中性粒细胞与淋巴细胞比值/血小板与淋巴细胞比值/纵横比Key words
multimodal ultrasound/inflammatory indicators/breast cancer/lymph node me-tastasis/predictive efficacy/neutrophil-to-lymphocyte ratio/platelet-to-lymphocyte ratio/aspect ratio分类
医药卫生引用本文复制引用
李俊辉,葛舒,王珏,张晴,杨春林..多模态超声联合免疫炎症指标预测乳腺癌腋窝淋巴结转移的价值[J].实用临床医药杂志,2025,29(15):1-5,5.基金项目
江苏省卫生健康委重点项目(K2019021) （K2019021）
