教育生物学杂志2025，Vol.13Issue(5)：366-370,375,6.DOI:10.3969/j.issn.2095-4301.2025.05.008
母亲咖啡饮用对婴儿早期神经精神发育和睡眠的影响
Impact of maternal coffee consumption on infants'early neuropsychiatric development and sleep patterns
摘要
Abstract
Objective To assess the impact of maternal coffee consumption on infants'early neuropsychiatric development and sleep patterns.Methods We selected 2-month-old infants who underwent routine health check-ups at 30 community health service centers in Shanghai between December 2022 and September 2023 and had complete data as study participants.A total of 596 infants were enrolled and categorized into the exposure group(n=302)and the control group(n=294)based on maternal coffee consumption before pregnancy,during pregnancy,and during breastfeeding.The exposure group was further subdivided into the pregnancy-only exposure subgroup(n=84)and the mixed exposure subgroup(n=218).General demographic information,ages and stages questionnaire-3(ASQ-3)assessment data,and sleep patterns of the infants were collected for retrospective analysis.Results There were no significant differences in the overall ASQ-3 screening results among the three groups(P>0.05).However,significant differences were observed in fine motor screening(H=8.36,P<0.05),primarily between the mixed exposure subgroup and the control group(H=23.29,P<0.05).Analysis of ASQ-3 influencing factors identified two significant protective factors:non-consumption of caffeinated beverages(OR=1.91,P<0.05)and higher gestational age(OR=1.24,P<0.05).The differences in sleep duration and nighttime waking between the exposure group and the control group were not significant(P>0.05).Notably,infants in the pregnancy-only exposure subgroup had longer daytime sleep[7.0(5.0,8.5)h]compared to the mixed exposure subgroup[6.0(5.0,8.0)h](H=-59.52,P<0.05).Conclusion Infants whose mothers consume coffee may experience altered early neuropsychiatric development.Maternal and child health professionals should provide evidence-based guidance to pregnant women regarding the moderate consumption of coffee or caffeinated beverages.关键词
咖啡因/婴儿/年龄与发育进程问卷/神经精神发育/睡眠Key words
caffeine/infants/ages and stages questionnaire/neuropsychiatric development/sleep引用本文复制引用
郎芳,张静亚,李文先,马腹婵,程苾恒..母亲咖啡饮用对婴儿早期神经精神发育和睡眠的影响[J].教育生物学杂志,2025,13(5):366-370,375,6.基金项目
中国疾病预防控制中心妇幼保健中心母婴营养与健康研究项目(2022FYH018) （2022FYH018）
