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Fusion genes in cancers:Biogenesis,functions,and therapeutic implications

Haiqiong Tang Mingjing Peng Longzheng Xia Wenjuan Yang Shizhen Li Jiewen Wang Yaqian Han Nayiyuan Wu Yanyan Tang Jinguan Lin Qianjin Liao Qiu Peng Yujuan Zhou Linda Oyang Shiming Tan Xianjie Jiang Zongyao Ren Xuemeng Xu Mengzhou Shen Haofan Li

基因与疾病（英文）2025，Vol.12Issue(5)：355-368,14.

基因与疾病（英文）2025，Vol.12Issue(5)：355-368,14.DOI:10.1016/j.gendis.2025.101536

Fusion genes in cancers:Biogenesis,functions,and therapeutic implications

Haiqiong Tang ¹Mingjing Peng ²Longzheng Xia ²Wenjuan Yang ²Shizhen Li ¹Jiewen Wang ³Yaqian Han ²Nayiyuan Wu ²Yanyan Tang ²Jinguan Lin ²Qianjin Liao ⁴Qiu Peng ²Yujuan Zhou ³Linda Oyang ²Shiming Tan ²Xianjie Jiang ²Zongyao Ren ²Xuemeng Xu ²Mengzhou Shen ³Haofan Li³

作者信息

1. The Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University/Hunan Cancer Hospital,Hunan Key Laboratory of Cancer Metabolism Changsha,Hunan 410013,China||University of South China,Hengyang,Hunan 421001,China
2. The Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University/Hunan Cancer Hospital,Hunan Key Laboratory of Cancer Metabolism Changsha,Hunan 410013,China||Hunan Engineering Research Center of Tumor Organoid Technology and Application,Public Service Platform of Tumor Organoids Technology,Changsha,Hunan 410013,China
3. The Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University/Hunan Cancer Hospital,Hunan Key Laboratory of Cancer Metabolism Changsha,Hunan 410013,China||University of South China,Hengyang,Hunan 421001,China||Hunan Engineering Research Center of Tumor Organoid Technology and Application,Public Service Platform of Tumor Organoids Technology,Changsha,Hunan 410013,China
4. Department of Oncology,Hunan Provincial People's Hospital(The First-Affiliated Hospital of Hunan Normal University),Changsha,Hunan 410005,China
折叠

摘要

关键词

BCR-ABL/Cancers/EML4-ALK/Fusion genes/PML-RARα

Key words

BCR-ABL/Cancers/EML4-ALK/Fusion genes/PML-RARα

引用本文复制引用

Haiqiong Tang,Mingjing Peng,Longzheng Xia,Wenjuan Yang,Shizhen Li,Jiewen Wang,Yaqian Han,Nayiyuan Wu,Yanyan Tang,Jinguan Lin,Qianjin Liao,Qiu Peng,Yujuan Zhou,Linda Oyang,Shiming Tan,Xianjie Jiang,Zongyao Ren,Xuemeng Xu,Mengzhou Shen,Haofan Li..Fusion genes in cancers:Biogenesis,functions,and therapeutic implications[J].基因与疾病（英文）,2025,12(5):355-368,14.

基金项目

This work was supported in part by grants from the Na-tional Natural Science Foundation of China(No.82302987,82303534,82203233,82202966,82173142),the Natural Science Foundation of Hunan Province,China(No.2024JJ4025,2023JJ60469,2023JJ40413,2023JJ40417,2023JJ30372,2023JJ30375),the Science and Technology Innovation Program of Hunan Province,China(No.2024RC3231,2023ZJ1122,2023RC3199,2023SK4034,2023RC1073),the Research Project of Health Commission of Hunan Province,China(No.R2023040,Z2023086,R2023093,202203034978,202202055318),and the Hunan Cancer Hospital Climb Plan(Hunan,China)(No.ZX2020001-3,YF2020002,2023NSFC-A001,2023NSFC-A002,2023NSFC-A004). （No.82302987,82303534,82203233,82202966,82173142）

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