实用临床医药杂志2025，Vol.29Issue(16)：9-13,5.DOI:10.7619/jcmp.20251524
多中心复杂海拔差异人群自发性脑出血早期血肿扩大的影响因素分析
Influencing factors of early hematoma expansion in spontaneous cerebral hemorrhage in multicenter population with complex altitude differences
摘要
Abstract
Objective To investigate the influencing factors for early hematoma enlargement(HE)in patients with spontaneous intracerebral hemorrhage(SICH).Methods A total of 311 pa-tients with SICH were selected as research subjects.Based on the occurrence of HE,they were divided into enlargement group and non-enlargement group.Clinical assessment indicators of patients with SICH were collected,and general information between the two groups was compared.The influencing factors for the occurrence of HE in patients with SICH were analyzed.Results Based on the presence of HE at a second CT examination within 6 to 12 hours,311 patients with SICH were divided into en-largement group(n=97)and non-enlargement group(n=214).Univariate analysis revealed signifi-cant differences between the two groups in terms of initial hematoma volume,regularity of hematoma margin,Glasgow Coma Scale(GCS)score,coagulation function,as well as the presence of swirl sign,lobulation sign,black hole sign,blend sign,lymphocyte count and neutrophil count(P＜0.05).Multivariate analysis indicated that GCS score,initial hematoma volume,history of antithrom-botic drug use,abnormal coagulation function and intracranial CT signs were independent influencing factors for HE(P＜0.05).Conclusion The occurrence of HE in patients with SICH is closely re-lated to GCS score,initial hematoma volume,history of antithrombotic drug use,abnormal coagulation function and intracranial CT signs.关键词
自发性脑出血/血肿扩大/影响因素/凝血功能/CT征象/格拉斯哥昏迷量表评分/淋巴细胞/初始血肿体积Key words
spontaneous intracerebral hemorrhage/hematoma enlargement/influencing factors/coagulation function/CT signs/Glasgow Coma Scale score/lymphocytes/initial hematoma volume分类
医药卫生引用本文复制引用
土旦达杰,杨藻,庄鹏,任霜,王建华,王晓宇,普布次仁..多中心复杂海拔差异人群自发性脑出血早期血肿扩大的影响因素分析[J].实用临床医药杂志,2025,29(16):9-13,5.基金项目
西藏自治区科技厅重点研发计划基金资助项目(XZ202501ZY0070) （XZ202501ZY0070）
