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HER3:Unmasking a twist in the tale of a previously unsuccessful therapeutic pursuit targeting a key cancer survival pathway

Omkar Desai Moeez Rathore Christina S.Boutros Michel'le Wright Elizabeth Bryson Kimberly Curry Rui Wang

基因与疾病（英文）2025，Vol.12Issue(4)：328-341,14.

基因与疾病（英文）2025，Vol.12Issue(4)：328-341,14.DOI:10.1016/j.gendis.2024.101354

HER3:Unmasking a twist in the tale of a previously unsuccessful therapeutic pursuit targeting a key cancer survival pathway

Omkar Desai ¹Moeez Rathore ²Christina S.Boutros ¹Michel'le Wright ²Elizabeth Bryson ²Kimberly Curry ²Rui Wang¹

作者信息

1. Department of Surgery,Case Western Reserve University,Cleveland,OH 44106,USA||Case Comprehensive Cancer Center,Case Western Reserve University,Cleveland,OH 44106,USA||Department of Surgery,Division of Surgical Oncology,University Hospitals Cleveland Medical Center,Cleveland,OH 44106,USA
2. Department of Surgery,Case Western Reserve University,Cleveland,OH 44106,USA||Case Comprehensive Cancer Center,Case Western Reserve University,Cleveland,OH 44106,USA
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摘要

关键词

Cancer/ErbB3/HER3/Neuregulin/Tumor microenvironment

Key words

Cancer/ErbB3/HER3/Neuregulin/Tumor microenvironment

引用本文复制引用

Omkar Desai,Moeez Rathore,Christina S.Boutros,Michel'le Wright,Elizabeth Bryson,Kimberly Curry,Rui Wang..HER3:Unmasking a twist in the tale of a previously unsuccessful therapeutic pursuit targeting a key cancer survival pathway[J].基因与疾病（英文）,2025,12(4):328-341,14.

基金项目

This work was supported by the National Institutes of Health(No.R00CA225756,R37CA278982 to R.W.)and the U.S.Department of Defense(No.HT9425-23-1-0657 to R.W.). （No.R00CA225756,R37CA278982 to R.W.）

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