军事医学2025，Vol.49Issue(8)：617-623,7.DOI:10.7644/j.issn.1674-9960.2025.08.009
感染性肺炎的靶向治疗新策略:基于免疫细胞的仿生纳米递药系统
Targeted therapeutic strategies for infectious pneumonia:immunocyte-derived biomimetic nano-drug delivery systems
田豪 1巴琪 1龚伟 2王玉丽 2杨阳 2高春生 2杨美燕2
作者信息
- 1. 军事科学院军事医学研究院,北京 100850||青岛大学药学院,山东青岛 266000
- 2. 军事科学院军事医学研究院,北京 100850
- 折叠
摘要
Abstract
Infectious pneumonia caused by bacteria,viruses,or other pathogenic microorganisms remains a huge threat to human health.Immunocyte-derived biomimetic nano-drug delivery systems can be used for drug delivery by taking advantage of the natural anti-inflammatory effect of immune cells and thus show great potential in lung-targeted therapy.This review begins by introducing different types of immune cells in the lung.The preparation methods of immunocyte-derived biomimetic nano-drug delivery systems and their applications in bacterial pneumonia,viral pneumonia,acute respiratory distress syndrome and cytokine storms are also reviewed.The review is expected to provide data for the targeted therapy of infectious pneumonia.关键词
仿生纳米递药系统/感染性肺炎/细胞膜包覆/细胞搭便车/肺部免疫Key words
biomimetic nano drug delivery system/infectious pneumonia/membrane coating/cell hitchhiking/pulmonary immunity分类
医药卫生引用本文复制引用
田豪,巴琪,龚伟,王玉丽,杨阳,高春生,杨美燕..感染性肺炎的靶向治疗新策略:基于免疫细胞的仿生纳米递药系统[J].军事医学,2025,49(8):617-623,7.
