岭南现代临床外科2025，Vol.25Issue(4)：215-219,5.DOI:10.3969/j.issn.1009-976X.2025.04.001
分析微波消融与肝切除术对AJCC Ⅰ期肝细胞癌患者预后影响—基于SEER数据库
Microwave ablation and hepatectomy on prognosis in patients with AJCC stage Ⅰ hepatocellular carcinoma based on the SEER database
江川 1刘睿 1蔡波 1蔡泽云1
作者信息
- 1. 怀化市中心医院肝胆外科,湖南 怀化 418000
- 折叠
摘要
Abstract
Objective To explore the optimal management strategy for AJCC stage Ⅰ hepatocellular carcinoma through a prognostic analysis of different surgical intervention strategies for patients in the SEER database.Methods Data of patients with AJCC stage Ⅰ hepatocellular carcinoma from January 1,2010,to December 31,2015,were retrieved and screened from the SEER database.Propensity score matching(1∶1 nearest neighbor)was used to balance confounding factors,dividing them into a micro-wave ablation group and a hepatectomy group(165 cases each)based on different surgical intervention strategies.Kaplan-Meier survival analysis was used to plot survival curves and calculate the mean survival time.Cox regression analysis was performed to identify the influencing factors of AJCC stage Ⅰ hepatocel-lular carcinoma-specific mortality.Results Kaplan-Meier survival curves showed that the mean survival time of the hepatic resection group was longer than that of the microwave ablation group,and the specific mortality rate of the hepatic resection group was lower than that of the microwave ablation group(P=0.046).Cox regression analysis showed that surgical intervention,degree of differentiation,marital status,and age were independent risk factors for AJCC stage Ⅰ hepatocellular carcinoma(all P<0.05).Conclusion Surgical approach is one of the independent risk factors for patients with AJCC stage Ⅰ hepatocellular carcinoma.Patients with AJCCstage Ⅰ hepatocellular carcinoma who undergo liver resection have a reduced cancer specific mortality.The prognosis of patients with AJCC stage Ⅰ hepatocellular carcinoma who undergo liver resection surgery is significantly higher than that of those who undergo microwave ablation surgery.关键词
肝细胞癌/AJCC Ⅰ期/微波消融/肝切除术/预后/SEER数据库Key words
hepatocellular carcinoma/AJCC stage Ⅰ/microwave ablation/hepatectomy/prognosis/SEER database分类
医药卫生引用本文复制引用
江川,刘睿,蔡波,蔡泽云..分析微波消融与肝切除术对AJCC Ⅰ期肝细胞癌患者预后影响—基于SEER数据库[J].岭南现代临床外科,2025,25(4):215-219,5.
