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翼状胬肉手术后并发症的机制和治疗策略

潘慧玲 吴双庆

国际眼科杂志2025,Vol.25Issue(10):1551-1559,9.
国际眼科杂志2025,Vol.25Issue(10):1551-1559,9.DOI:10.3980/j.issn.1672-5123.2025.10.02

翼状胬肉手术后并发症的机制和治疗策略

Mechanisms and treatment strategies for postoperative complications of pterygium surgery

潘慧玲 1吴双庆2

作者信息

  • 1. (310053)中国浙江省杭州市,浙江中医药大学第二临床医学院||(312500)中国浙江省新昌县人民医院
  • 2. (325027)中国浙江省温州市,温州医科大学附属眼视光医院国家眼部疾病临床医学研究中心
  • 折叠

摘要

Abstract

Pterygium,a common ocular surface disorder characterized by the abnormal growth of conjunctival tissue onto the cornea,often necessitates surgical excision as its primary treatment.While effective,pterygium surgery is frequently associated with a spectrum of postoperative complications that significantly impact patient prognosis and quality of life.This comprehensive review systematically analyzes the classification,underlying pathophysiological mechanisms,and associated risk factors of these complications,with a particular focus on less commonly explored entities such as postoperative granuloma(PPG),corneal dellen,and scleral necrosis,alongside the more prevalent issue of recurrence.We delineate these complications based on their temporal presentation(early,intermediate,and late),and provide an in-depth analysis of general and specific contributing factors,including surgical trauma,individual patient characteristics,surgical technique,and perioperative management.Furthermore,this review synthesizes advancements in preventive strategies and therapeutic interventions,encompassing refined surgical techniques[e.g.,femtosecond laser-assisted pterygium surgery(FLAPS),pterygium extended removal followed by extended conjunctival transplant(P.E.R.F.E.C.T.)technique,Tissue Tuck technique],judicious application of adjuvant therapies[e.g.,mitomycin C(MMC),5-fluorouracil(5-FU),corticosteroids,anti-vascular endothelial growth factor(VEGF)agents],and optimized postoperative care protocols.By consolidating current evidence and identifying future research priorities,this review aims to provide ophthalmologists with a valuable theoretical foundation to guide individualized surgical planning,dynamic postoperative management,and ultimately minimize complications and improve patient satisfaction.

关键词

翼状胬肉/术后并发症/复发/肉芽肿/巩膜坏死/辅助治疗/飞秒激光辅助翼状胬肉手术

Key words

pterygium/postoperative complication/recurrence/granuloma/scleral necrosis/adjuvant therapy/femtosecond laser-assisted pterygium surgery

引用本文复制引用

潘慧玲,吴双庆..翼状胬肉手术后并发症的机制和治疗策略[J].国际眼科杂志,2025,25(10):1551-1559,9.

国际眼科杂志

1672-5123

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