国际眼科杂志2025，Vol.25Issue(10)：1566-1573,8.DOI:10.3980/j.issn.1672-5123.2025.10.04
折叠式球囊巩膜外加压与传统巩膜扣带术治疗实验性视网膜脱离的疗效比较
Efficacy comparison of foldable capsular body with scleral buckling in treating experimental retinal detachment
摘要
Abstract
AIM:To compare the effectiveness of foldable capsular body(FCB)with traditional scleral buckling(SB)in the treatment of experimental retinal detachment animal models. METHODS:After successfully establishing rhegmatogenous retinal detachment(RRD)animal models,24 New Zealand white rabbits were randomly divided into three groups(RRD models group,SB group,and FCB group),with 8 rabbits in each group.The FCB and SB groups underwent SB and FCB surgeries for the RRD animal models,while the RRD models group only consists of RRD models without any surgical intervention during the follow-up period.The follow-up duration was 3 mo.Wide-field neonatal fundus imaging system and ophthalmic B-ultrasound were used to assess the fundus conditions before and after surgery.The Icare ® TONOVET Plus tonometer was utilized to evaluate intraocular pressure changes before and after surgery.The Eaton and Draize scoring systems were selected to monitor postoperative inflammatory reactions. RESULTS:The retinal reattachment rates in the FCB and SB groups were 87.5％and 75.0％,respectively,with no statistically significant difference between the groups(P＞0.05).The intraocular pressure in both the FCB and SB groups increased postoperatively compared to preoperative levels(P＜0.01),and there were no significant differences in intraocular pressure at any time points during the follow-up period between the groups(P＞0.05).The intraocular pressure in the RRD models group remained at a low level throughout the follow-up period.The average surgical time for the FCB group was 16.87±2.29 min,which was shorter than 46.25±4.74 min in the SB group(t=-15.166,P＜0.001).According to the Eaton and Draize scoring systems,the FCB group had lower grades of conjunctival hyperemia and edema in the early postoperative period compared to the SB group,indicating milder inflammatory reactions(P＜0.05). CONCLUSION:Both FCB and SB are effective in treating experimental RRD.Compared to SB,FCB is simpler to operate,and also has a shorter surgical time and milder postoperative inflammatory reactions.关键词
孔源性视网膜脱离/折叠式球囊/巩膜扣带术/实验性视网膜脱离Key words
rhegmatogenous retinal detachment/foldable capsular body/scleral buckling/experimental retinal detachment引用本文复制引用
董毅凡,田学敏,张百珂,贾雍,杨帆,郭丽莎,张向阳,卢聪,张中浩,武海燕..折叠式球囊巩膜外加压与传统巩膜扣带术治疗实验性视网膜脱离的疗效比较[J].国际眼科杂志,2025,25(10):1566-1573,8.基金项目
河南省自然科学基金项目(No.202300420066) Natural Science Foundation of Henan Province(No.202300420066) （No.202300420066）
