视觉线索训练对帕金森病伴冻结步态患者抑制性控制功能的影响OA

Objective To explore the effect of visual cues rehabilitation on the control function of freezing of gait(FOG)in Parkinson's disease(PD)and analyze the correlation between control abilities and motor status.Methods Seventy-two patients with PD and FOG symptoms were recruited and divided into a conventional drug treatment group(control group)and a visual cues rehabilitation care treatment group(experimental group)by a simple randomization method.Functional scores of the inhibitory control task(Go/NoGo),FOG questionnaire(FOG-Q)scale,and the mini-balance evaluation systems test(mini-BESTest)were collected before treatment and one week after intervention.Before the intervention,the two-sample t-test was employed to compare the two groups,and after that,an analysis of variance was employed to compare the groups while baseline values were controlled as covariates.The Pearson correlation was used to analyze the correlation between cognitive control and motor function.Results There were no significant differences in gender,age,education level and duration of disease between the two groups(P>0.05).After visual cues rehabilitation nurs-ing,NoGo error rate was significantly decreased(F=4.471,P=0.038),FOG-Q score significantly decreased(F=31.477,P<0.001),and mini-BESTest score significantly increased(F=40.163,P<0.001)in the experimen-tal group.The freezing gait symptom scores were positively correlated with NoGo error rate of the inhibitory control function(r=0.480,P=0.005)in the experimental group.Conclusion Visual cues rehabilitation for PD with FOG patients may help patients restore their inhibitory control function,improve frozen gait symptoms and enhance balance functions.