实用肝脏病杂志2025，Vol.28Issue(5)：711-714,4.DOI:10.3969/j.issn.1672-5069.2025.05.018
代谢相关脂肪性肝病患者肝组织学表现研究
Liver histo-pathological manifestation in patients with metabolic fatty liver disease:An analysis of 35 cases
摘要
Abstract
Objective The purpose of this study was to analyze the histo-pathological manifestations of liver biopsy tissues in patients with metabolic-associated fatty liver disease(MAFLD).Methods In this study,a retrospective analysis was performed to collect liver tissue data in 35 patients with MAFLD.All patients underwent liver biopsies in our hospital between August 2017 and December 2022,and the histological manifestations of liver tissues were observed.Results Of the 35 patients with MAFLD,liver histo-pathological examination showed liver steatosis F0 in 8 cases(22.9％),F1 in 16 cases(45.7％),F2 in 5 cases(14.3％)and F3 in 6 cases(17.1％),e.g.,liver steatosis in 27 cases(77.1％),of them,the MAFLD activity score(MAS)≥ 5,suggesting MASH in 11 cases(31.4％);hepatocellular ballooning in 26 cases(74.4％),with and without lobular inflammation in 32 cases(91.4％)and in 3 cases(8.6％),of them,grade 1 in 14 cases(40.0％),grade 2 in 12 cases(34.3％)and grade 3 in 6 cases(17.1％);Mallory-body was found in 5 cases(14.3％);no liver fibrosis in 5 cases(14.3％),significant liver fibrosis in 16 cases(45.7％)and advanced liver fibrosis in 14 cases(40.0％).Conclusion Liver biopsy is important for clarification of histopathological changes,which might help clinicians make an appropriate measures to deal with it.关键词
代谢相关脂肪性肝病/肝穿刺活检/组织病理学Key words
Metabolism-related fatty liver disease/Liver biopsy/Histopathology引用本文复制引用
杨欢,袁宏伟,奇丽娜,陈平..代谢相关脂肪性肝病患者肝组织学表现研究[J].实用肝脏病杂志,2025,28(5):711-714,4.基金项目
国家自然科学基金资助项目(编号:82260115) （编号:82260115）
内蒙古自治区自然科学基金资助项目(编号:2024LHMS08012) （编号:2024LHMS08012）
内蒙古医科大学附属医院院级科研项目资助(编号:2023NYFYTS019) （编号:2023NYFYTS019）
