上海预防医学2025，Vol.37Issue(7)：556-561,6.DOI:10.19428/j.cnki.sjpm.2025.25044
上海市动物源性食品中全氟化合物污染健康风险评估
Health risk assessment of per-and polyfluoroalkyl substances contamination in animal-derived foods in Shanghai
摘要
Abstract
[Objective]To analyze the current status of per-and polyfluoroalkyl substances(PFASs)contamination in animal-derived foods in Shanghai and to assess the risk of dietary exposure among local residents,thereby providing a scientific basis for future dietary safety and risk management.[Methods]A total of 300 commonly consumed animal-derived food samples were collected in Shanghai in 2023 and tested for 17 types of PFASs.Based on local dietary consumption data,the weekly exposure intake(EWI)of four representative PFASs was calculated using the exposure assessment model recommended by Food and Agriculture Organization(FAO)and the World Health Organization(WHO).The calculated EWI was compared with the tolerable weekly intake(TWI)set by the European Food Safety Authority(EFSA)to assess the health risks associated with dietary intake of PFASs.[Results]The predominant PFASs detected in aquatic products were PFUnDA(98.67%),PFTrDA(98.00%),and PFOS(95.33%),with PFUnDA having the highest median mass fraction(0.378 ng·g-1).In meat samples,PFBA(54.17%),PFOA(20.83%),and PFOS(18.33%)were mainly detected,with PFBA showing the highest median mass fraction(0.027 ng·g-1).In egg samples,the most frequently detected compounds were PFBA(90.00%),PFOA(63.33%),PFOS(50.00%),PFDA(50.00%),PFNA(50.00%),and PFHxDA(50.00%),with PFBA again having the highest median mass fraction(0.068 ng·g-1).The median mass fractions of the four key PFASs(PFOA,PFOS,PFNA,and PFHxS)in aquatic products were significantly higher than those in meat products and eggs(all P<0.001),and there were statistically significant differences in the median mass fractions of the four PFASs among different types of aquatic products(all P<0.05).The EWI of the four PFASs was 2.970 ng·kg-1 for the mean consumption group and 6.676 ng·kg-1 for the high consumption group(P95),with females having higher EWI values than males.[Conclusion]PFOS,PFOA,and PFBA are the major PFAS contaminants in animal-derived foods consumed by Shanghai residents,with aquatic products having the highest levels of contamination.The EWIs of four PFASs among Shanghai residents did not exceed EFSA's recommended TWI at average consumption levels.However,the EWIs for high-consumption populations exceeded the EFSA-recommended TWI,posing potential health risks to these populations.Aquatic products contribute the most to dietary PFAS exposure.It is necessary to strengthen PFAS monitoring in aquatic products and conduct targeted risk assessments for high-consumption groups.关键词
全氟化合物/污染现状/膳食暴露/风险评估/动物源性食品Key words
per-and polyfluoroalkyl substance/pollution status/dietary exposure/risk assessment/animal-derived food分类
医药卫生引用本文复制引用
谷臣琳,杨京津,罗宝章,邱丹萍,刘弘,蔡华..上海市动物源性食品中全氟化合物污染健康风险评估[J].上海预防医学,2025,37(7):556-561,6.基金项目
上海市加强公共卫生体系建设三年行动计划(2023-2025年)重点学科建设项目(GWVI-11.1-42) （2023-2025年）
