生命科学研究2025，Vol.29Issue(4)：312-316,5.DOI:10.16605/j.cnki.1007-7847.2024.10.0180
抗氧化剂在2型糖尿病心脏并发症中的作用
Roles of Antioxidants in Cardiac Complications of Type 2 Diabetes Mellitus
摘要
Abstract
Type 2 diabetes mellitus(T2DM)is a globally prevalent metabolic disorder,and patients often suf-fer from various cardiac complications,the occurrence of which is closely associated with oxidative stress.Oxidative stress has been demonstrated to result in cellular damage,inflammatory responses,and endothelial dysfunction,thereby increasing the risk of cardiovascular diseases.Antioxidants have emerged as a potential therapeutic agent,alleviating the occurrence and development of T2DM-related cardiac complications by re-ducing cellular damage,regulating inflammatory responses,and improving endothelial function.This article provides a comprehensive review of the mechanisms of action of antioxidants in T2DM-related cardiac com-plications,current clinical research progress,and future application prospects,aiming to offer valuable insights for clinical practice and to facilitate the application of antioxidants in the treatment of cardiac complications.关键词
抗氧化剂/2型糖尿病(T2DM)/心脏并发症/氧化应激/临床应用Key words
antioxidant/type 2 diabetes mellitus(T2DM)/cardiac complication/oxidative stress/clinical ap-plication分类
生物科学引用本文复制引用
方丽佳,王溪,桑怡斐,石芸..抗氧化剂在2型糖尿病心脏并发症中的作用[J].生命科学研究,2025,29(4):312-316,5.基金项目
河北省卫生健康委员会医学科学研究课题计划项目(20191501,20180695) （20191501,20180695）
河北省自然科学基金面上项目(H2023206511) （H2023206511）
