生命科学研究2025，Vol.29Issue(4)：317-325,338,10.DOI:10.16605/j.cnki.1007-7847.2025.01.0115
戊型肝炎的流行、诊断与预防
Epidemiology,Diagnosis,and Prevention of Hepatitis E
摘要
Abstract
Hepatitis E(HE)is an acute viral hepatitis caused by hepatitis E virus(HEV),typically manifes-ting as a self-limiting disease.However,growing evidence in recent years suggests that HEV infection may progress to chronicity in certain immunocompromised individuals,ultimately leading to severe hepatitis,cir-rhosis,and liver failure.Among high-risk groups,such as pregnant women and organ transplant recipients,HEV infection is associated with an alarmingly high mortality rate,emerging as a global public health con-cern.Therefore,adopting effective diagnostic methods for early screening,diagnosis,and monitoring of HEV infection is critical for HE prevention,control,and treatment.This paper summarizes the biological charac-teristics of HEV and highlights the current high-risk status of HEV infection in human populations.It also introduces the clinical diagnostic indicators,common diagnostic methods,as well as preventive and thera-peutic approaches for HE.The review aims to offer new insights for achieving the goal of reducing and ulti-mately eliminating viral hepatitis in China.关键词
戊型肝炎病毒(HEV)/流行病学特征/诊断技术/预防策略/治疗进展Key words
hepatitis E virus(HEV)/epidemiologic feature/diagnostic technique/prevention strategy/thera-peutic advancement分类
生物科学引用本文复制引用
张鑫兰,艾湘君,刘如石,朱建蓉,万婷,胡锦莲,刘艳..戊型肝炎的流行、诊断与预防[J].生命科学研究,2025,29(4):317-325,338,10.基金项目
国家自然科学基金资助项目(31072141) （31072141）
湖南省自然科学基金项目(12JJ2013) （12JJ2013）
