天津中医药2025，Vol.42Issue(9)：1122-1126,5.DOI:10.11656/j.issn.1672-1519.2025.09.06
针灸强刺激疗法联合盐酸消旋山莨菪碱注射液治疗泌尿系结石性肾绞痛的镇痛效果研究
Research on analgesic effect of acupuncture and moxibustion strong stimulation therapy combined with raceanisodamine hydrochloride injection in the treatment of urinary calculi renal colic
摘要
Abstract
[Objective]To explore the analgesic effect of acupuncture and moxibustion strong stimulation therapy combined with raceanisodamine hydrochloride injection in the treatment of urinary calculi renal colic and its influence on serum total antioxidant capacity(TAC),ischemia modified albumin(IMA)and myoglobin(MYO)levels.[Methods]From August 2023 to September 2024,80 patients with urinary calculi renal colic in Shijiazhuang Hospital of Traditional Chinese Medicine were included and received routine stone removal.According to the simplified random method,the patients were divided into conventional group(raceanisodamine hydrochloride injection treatment,40 cases)and acupuncture and moxibustion group(acupuncture and moxibustion strong stimulation therapy combined with raceanisodamine hydrochloride injection treatment,40 cases).The analgesic effect(pain relief rate and pain attack frequency after 30 min of medication,analgesic time),pain scores[numerical rating scale(NRS),Wong-Baker facial expression scale,simplified McGill pain questionnaire(SF-MPQ)]and serum pain stress factors[substance P,prostaglandin E2(PGE2)]and TAC,IMA and MYO before and after treatment were compared between groups,and the incidence rates of adverse reactions were counted.[Results]After 30 min of medication,the pain relief rate and analgesic time in acupuncture and moxibustion group were significantly higher or longer than those in conventional group(P＜0.05 or P＜0.01),and the pain attack frequency was significantly less than that in conventional group(P＜0.05).After treatment,the scores of of NRS,Wong-Baker facial expression scale and SF-MPQ and levels of serum substance P,PGE2,IMA and MYO in the two groups were significantly decreased(P＜0.05),and the above scores and levels were significantly lower in acupuncture and moxibustion group than those in conventional group(P＜0.05 or P＜0.01).After treatment,the level of TAC was significantly increased in both groups(P＜0.05),and the level in acupuncture and moxibustion group was significantly higher than that in conventional group(P＜0.05).There was no significant difference in the incidence of adverse reactions between acupuncture and moxibustion group(12.50％)and conventional group(7.50％,P＞0.05).[Conclusion]Acupuncture and moxibustion strong stimulation therapy combined with raceanisodamine hydrochloride injection has a good analgesic effect in the treatment of urinary calculi renal colic,and it can effectively improve the levels of serum pain stress factors and oxidative injury factors,and it is safe and effective.关键词
针灸疗法/针刺/镇痛/泌尿系结石/肾绞痛Key words
acupuncture and moxibustion therapy/acupuncture/analgesia/urinary calculi/renal colic分类
医药卫生引用本文复制引用
赵秋芳,贾云燕,侯书恒,臧红敏,李杨,崔颖,韩毅,王帆..针灸强刺激疗法联合盐酸消旋山莨菪碱注射液治疗泌尿系结石性肾绞痛的镇痛效果研究[J].天津中医药,2025,42(9):1122-1126,5.基金项目
河北省中医药类科学研究课题计划项目(2024374). （2024374）
