摘要
Abstract
Objective:To synthesize and integrate existing literature to evaluate the prevalence of uterine atony-related postpartum hemorrhage(UAPPH)and to explore the associ-ated risk factors for this postpartum complication.Methods:A systematic search was conducted in PubMed,Web of Science,China National Knowledge Infrastructure(CNKI),and Wanfang databases.The included studies comprised randomized controlled trials(RCTs),prospective or retrospective cohort studies,and case-control studies that reported at least one risk factor associ-ated with UAPPH.Eligible studies were screened based on inclusion and exclusion criteria,fol-lowed by quality assessment and data extraction.Statistical analyses were performed using Stata 15.0.Results:A total of 18 studies were included,among which 13 studies reported the preva-lence of UAPPH,covering 5 495 572 pregnant women,with a pooled prevalence of 0.03(95%CI:0.02～0.03).The identified risk factors for UAPPH included advanced maternal age(OR=1.51,95%CI:0.99～2.30),gestational hypertension(OR=2.53,95%CI:1.85～3.46),multiple gestation(OR=2.46,95%CI:1.85～3.27),primiparity(OR=0.89,95%CI:0.40～2.00),prolonged labor(OR=3.09,95%CI:1.82～5.23),fetal macrosomia(OR=1.66,95%CI:1.14～2.41),placental abnormalities(OR=5.56,95%CI:3.02～10.20),cesarean sec-tion(OR=1.51,95%CI:0.68～3.36),oxytocin use(OR=1.43,95%CI:1.15～1.78),and preeclampsia(OR=1.01,95%CI:0.52～1.97).Conclusion:Gestational hypertension,multi-ple gestation,prolonged labor,fetal macrosomia,placental abnormalities,and oxytocin use were significantly associated with the occurrence of uterine atony-related postpartum hemorrhage may be key risk factors of postpartum haemorrhage due to contraction weakness.These findings high-light the importance of early risk assessment and targeted clinical interventions to reduce the in-cidence of postpartum hemorrhage due to uterine atony and improve maternal outcomes.关键词
产后出血/宫缩乏力性/发生率/危险因素/Meta分析Key words
Postpartum hemorrhage/Uterine fatigue/The incidence rate/Risk factors/Meta-analysis分类
医药卫生
