中国医疗设备2025，Vol.40Issue(9)：129-133,5.DOI:10.3969/j.issn.1674-1633.20242039
能谱CT多参数成像在阴性胆囊结石诊断中的应用价值
Value of Spectral CT Multiparametric Imaging in the Diagnosis of Negative Gallbladder Stones
摘要
Abstract
Objective To explore the value of spectral CT's single-energy imaging,spectral curve,and atomic number in the diagnosis of negative gallbladder stones.Methods Imaging data of 76 patients with suspected negative gallbladder stones were retrospectively collected,and all patients underwent cholecystectomy,with surgical results as the reference standard.Differences in 40 keV single-energy images,spectral curve slopes,and effective atomic numbers between negative gallbladder stones and bile were compared.The diagnostic efficacy of 40 keV single-energy images,spectral curves,and effective atomic numbers for distinguishing negative gallbladder stones from bile was analyzed using receiver operating characteristic(ROC)curves.Results At 40 keV,the effective atomic number of negative gallbladder stones was 6.12±0.37,while that of bile was 7.45±0.41,with a statistically significant difference(P<0.05).The CT value of negative gallbladder stones was(-40.12±12.67)HU,and that of bile was(5.78±14.89)HU,showing a statistically significant difference(P<0.05).The spectral curve slope of negative gallbladder stones was-1.58±0.39,compared with 0.27±0.12 for bile,with a statistically significant difference(P<0.05).ROC curve analysis showed that the areas under the curve of 40 keV single-energy images,spectral curves,and atomic number maps were 0.940,0.951,and 0.974,respectively,with sensitivities and specificities of 88.89%and 84.21%,92.31%and 91.12%,100%and 96.11%.Conclusion Spectral CT multiparametric imaging is helpful for early detection of gallbladder stones,guides clinical treatment decisions,reduces the risk of misdiagnosis and missed diagnosis,and has a positive impact on patient treatment and prognosis.关键词
阴性胆囊结石/能谱CT成像/能谱曲线/原子序数图/虚拟单能量/多参数成像Key words
negative gallbladder stones/spectral CT imaging/spectral curve/atomic number map/virtual single energy/multiparametric imaging分类
医药卫生引用本文复制引用
陈宗桂,李禹睿,钟志明,魏宁宁,张英俊..能谱CT多参数成像在阴性胆囊结石诊断中的应用价值[J].中国医疗设备,2025,40(9):129-133,5.基金项目
湖南省自然科学基金青年项目(2021JJ40385) （2021JJ40385）
湖南省教育厅一般项目(22C1183). （22C1183）
