疑难病杂志2025，Vol.24Issue(9)：1036-1039,4.DOI:10.3969/j.issn.1671-6450.2025.09.003
参松养心胶囊联合利伐沙班治疗气阴两虚型中高危心房颤动患者的疗效研究
Clinical study on Shensong Yangxin Capsule combined with rivaroxaban in the treatment of middle and high risk at-rial fibrillation patients with deficiency of both qi and yin
摘要
Abstract
Objective To explore the clinical efficacy of Shensong Yangxin Capsule combined with rivaroxaban in the treatment of middle and high risk atrial fibrillation with deficiency of both qi and yin.Methods From June 2022 to June 2024,100 patients with moderate and high-risk atrial fibrillation of deficiency of both qi and yin were selected and divided in-to treatment group and control group according to random envelope and double-blind method,with 50 cases in each group.The control group was treated with rivaroxaban,while the treatment group was treated with Shensong Yangxin Capsule.The clinical efficacy and incidence of adverse reactions of the two groups were evaluated.The TCM syndrome score,inflammatory factors[Interleukin-6(IL-6),High-sensitivity C-reactive protein(hs-CRP)],Insulin-like growth factor(IGF-1),Thyroid stimu-lating hormone(TSH)and P-selectin(GPM-140)were compared between the two groups before and after treatment.Results The effective rate in the treatment group was significantly higher than that in the control group(x2/P=6.859/＜0.001).After treatment,the scores of TCM syndromes,IL-6,hs-CRP,IGF-1,TSH and GMP-140 in the treatment group were lower than those in the control group(t/P=5.378/＜0.001,9.444/＜0.001,7.155/＜0.001,5.602/＜0.001,7.344/＜0.001,9.029/＜0.001).There was no significant difference in adverse reactions between the treatment group and the control group(P＞0.05).Conclusion Shensong Yangxin Capsule combined with rivaroxaban can effectively control the symptoms of patients with atrial fibrillation of deficiency of both qi and yin,improve TCM syndromes,and reduce the risk of inflammatory factors and stroke.关键词
心房颤动/气阴两虚型/参松养心胶囊/利伐沙班/炎性因子Key words
Atrial fibrillation/Deficiency of both qi and yin/Shensong Yangxin Capsule/Rivaroxaban/Inflammatory factor分类
医药卫生引用本文复制引用
梁迪赛,包心仪,刘斯晗,袁丁..参松养心胶囊联合利伐沙班治疗气阴两虚型中高危心房颤动患者的疗效研究[J].疑难病杂志,2025,24(9):1036-1039,4.基金项目
广东省医学会临床科研基金项目(A202301009) Clinical Research Fund Project of Guangdong Medical Association(A202301009) （A202301009）
