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非洲猪瘟病毒减毒活疫苗研究进展

吕家轩于家荣左媛媛戈胜强郑龙三徐天刚李金明钱莺娟王志亮

中国动物检疫2025，Vol.42Issue(9)：49-56,63,9.

中国动物检疫2025，Vol.42Issue(9)：49-56,63,9.DOI:10.3969/j.issn.1005-944X.2025.09.009

非洲猪瘟病毒减毒活疫苗研究进展

Advances in Attenuated Live Vaccines against African Swine Fever Virus

吕家轩 ¹于家荣 ²左媛媛 ²戈胜强 ²郑龙三 ³徐天刚 ²李金明 ²钱莺娟 ³王志亮²

作者信息

1. 南京农业大学动物医学院,教育部动物健康与食品安全国际合作联合实验室,江苏南京 210095||中国动物卫生与流行病学中心,国家非洲猪瘟参考实验室,山东青岛 266032
2. 中国动物卫生与流行病学中心,国家非洲猪瘟参考实验室,山东青岛 266032
3. 南京农业大学动物医学院,教育部动物健康与食品安全国际合作联合实验室,江苏南京 210095
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摘要

Abstract

African swine fever(ASF)is a highly contagious disease caused by African swine fever virus(ASFV),posing a severe threat to global pig industry,which should be prevented and controlled by vaccines,particularly attenuated live vaccines with strong immunogenicity and high protective efficacy.Here,the advances in attenuated live vaccines against ASF were summarized,including development strategies based on naturally attenuated strains,artificially recombinant attenuated strains and cell-passaged attenuated strains.Challenges faced by vaccine development were analyzed,and future direction of vaccine development was deeply discussed,aiming to guide further researches of ASF vaccines.

关键词

非洲猪瘟/减毒活疫苗/疫病防控/疫苗研发

Key words

ASF/attenuated live vaccine/disease prevention and control/research and development of vaccines

分类

农业科技

引用本文复制引用

吕家轩,于家荣,左媛媛,戈胜强,郑龙三,徐天刚,李金明,钱莺娟,王志亮..非洲猪瘟病毒减毒活疫苗研究进展[J].中国动物检疫,2025,42(9):49-56,63,9.

基金项目

国家重点研发计划项目(2022YFD1800500) （2022YFD1800500）

中国动物检疫

ISSN：1005-944X

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