中国输血杂志2025,Vol.38Issue(9):1127-1138,12.DOI:10.13303/j.cjbt.issn.1004-549x.2025.09.001
血小板制剂细菌污染监测与防控中国专家共识
Chinese expert consensus on monitoring,prevention,and control of bacterial contamination in platelets
北京医学会输血医学分会 1汪德清 1夏荣 1张晰 1付涌水 1白求恩公益基金会输血医学专家委员会 1罗圆圆 1马春娅 1黄霞 1章怿 1何苗 1于洋 1王勇1
作者信息
摘要
Abstract
Platelet transfusion plays a critical role in the treatment of hematologic diseases,severe illnesses and malig-nancies.However,the unique storage temperature(22±2℃)makes it the most susceptible blood component to bacterial contamination,which may lead to life-threatening sepsis or even death in recipients.In China,the monitoring and preven-tion of platelet bacterial contamination faces a series of challenges,including low testing coverage,insufficient technology a-doption,and a lack of standardized protocols.To address these issues,the Transfusion Medicine Branch of Beijing Medical Association and the Transfusion Medicine Expert Committee of the Bethune Charitable Foundation jointly organized a multi-disciplinary panel of over 200 experts from across China,specializing in transfusion medicine,microbiology,and infection prevention and control.The panel conducted a systematic review of domestic and international literature(January 1970 to A-pril 2025).Utilizing the GRADE evidence classification system and considering China's specific context,the panel devel-oped 17 evidence-based recommendations spanning surveillance technologies,operational standards,risk assessment,and digital solutions.These recommendations aim to provide a scientific foundation for establishing a comprehensive national framework for platelet bacterial contamination monitoring and prevention.关键词
血小板制剂/细菌污染/血液安全/监测体系/临床风险/防控策略Key words
platelets/bacterial contamination/blood safety/monitoring system/clinical risk/prevention and control strategies分类
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北京医学会输血医学分会,汪德清,夏荣,张晰,付涌水,白求恩公益基金会输血医学专家委员会,罗圆圆,马春娅,黄霞,章怿,何苗,于洋,王勇..血小板制剂细菌污染监测与防控中国专家共识[J].中国输血杂志,2025,38(9):1127-1138,12.