中国输血杂志2025，Vol.38Issue(9)：1183-1187,5.DOI:10.13303/j.cjbt.issn.1004-549x.2025.09.010
不同用量的等渗洗涤液对颅脑手术自体血回收质量的影响
Impact of different volumes of isotonic washing solution on the quality of intraoperative autologous blood salvage in craniocerebral surgery
摘要
Abstract
Objective To investigate the effect of different volumes of isotonic washing solution(0.9%NaCl)on the quality of intraoperative autologous blood salvage in craniocerebral surgery.Methods Thirty patients who underwent neuro-surgical procedures with intraoperative salvaged blood volumes exceeding 800 mL between August 2022 and July 2024 were enrolled as study subjects.The salvaged blood was divided into four groups:group A,group B,group C,and group D.Group A was washed with 500 mL of isotonic solution(blood-to-washing solution ratio of 1∶2),group B with 1000 mL(rati-o of 1∶4),and group C with 1 500 mL(ratio of 1∶6).After centrifugation,the washed blood was stored in designated blood bags(A,B,and C,respectively).Blood gas analysis was performed on 5 mL samples obtained from the centrifuged blood in groups A,B,and C,and from the unwashed blood in the reservoir of the control group(group D).Parameters in-cluding red blood cell(RBC)count,pH,hemoglobin(Hb),hematocrit(HCT),potassium ion(K+),sodium ion(Na+),and lactate levels were also measured using these samples.Additionally,blood samples from each group were ex-amined microscopically to assess red blood cell morphology.Results No significant differences were observed among groups A,B,and C in terms of RBC recovery rate,HCT,Na+concentration,or lactate clearance rate(P＞0.05).All three groups exhibited a reduction in pH,with group C showing a more pronounced decrease compared to groups A and B.Simi-larly,K+clearance was achieved in all groups,with group C demonstrating superior efficiency.Microscopic analysis re-vealed a reduction in spiculated red blood cells across all groups,with group C achieving the highest clearance rate.Con-clusion Group C(washed with 1 500 mL solution)demonstrated optimal performance in reducing pH levels,clearing K+,and removing spherocytes,while maintaining red blood cell recovery rate.Additionally,it did not significantly increase the risk of hypernatremia in critically ill neurosurgical patients,making it more suitable for craniocerebral surgeries.关键词
自体血回收/等渗洗涤液/血液质量/红细胞回收率Key words
autologous blood salvage/isotonic saline washing solution/blood quality/RBC recovery rate分类
医药卫生引用本文复制引用
容芳松,何嘉凝,郑秋艳,何后仲,黄鸿辉..不同用量的等渗洗涤液对颅脑手术自体血回收质量的影响[J].中国输血杂志,2025,38(9):1183-1187,5.基金项目
钦州市科学研究与技术开发计划项目(20223011) （20223011）
