中国实用内科杂志2025，Vol.45Issue(8)：652-655,4.DOI:10.19538/j.nk2025080106
抗骨质疏松治疗中维生素D的合理使用
Rational use of vitamin D in the treatment of osteoporosis
摘要
Abstract
With the accelerated aging of the population in China,osteoporosis has emerged as a critical public health problem that significantly threatens the health of the elderly.Vitamin D deficiency or insufficiency is widespread in the general population,particularly among postmenopausal women and older adults,thereby increasing the risk of osteoporosis.Adequate vitamin D status is fundamental for maintaining bone health.However,as its primary source relies on synthesis in the skin upon sun exposure,insufficient sun exposure often restricts vitamin D production,making vitamin D deficiency highly prevalent.Consequently,critical questions requiring urgent resolution in clinical practice arise:What dosage of vitamin D is required for patients with osteoporosis to maintain skeletal health?How should vitamin D be supplemented scientifically as fundamental therapy for osteoporosis?This review focuses on vitamin D supplementation strategies for patients with osteoporosis,including suitable dosage and supplementation regimens,to ensure the therapeutic efficacy of anti-osteoporosis medications.关键词
骨质疏松症/维生素D/活性维生素D/合理用药Key words
osteoporosis/vitamin D/active form of vitamin D/rational drug use分类
医药卫生引用本文复制引用
许丰,谢忠建..抗骨质疏松治疗中维生素D的合理使用[J].中国实用内科杂志,2025,45(8):652-655,4.基金项目
国家重点研发计划(2021YFC2501700,2021YFC2501705) （2021YFC2501700,2021YFC2501705）
国家自然科学基金(82171580,82100494) （82171580,82100494）
湖南省自然科学基金(2021JJ30035,2025JJ40097,2022JJ40721) （2021JJ30035,2025JJ40097,2022JJ40721）
