中国医学前沿杂志（电子版）2025，Vol.17Issue(7)：56-59,4.DOI:10.12037/YXQY.2025.07-08
抗结核治疗1个月内服用双环醇的疗效分析
Analysis of the therapeutic effect of bicyclol within one month for anti-tuberculosis treatment
摘要
Abstract
Objective To analyze the the effect of bicyclol on tuberculosis(TB)patients within one month of starting anti-TB treatment.Methods A retrospective study including TB patients from the hospital information system of Beijing Chest Hospital,Capital Medical University between January 2010 and December 2020 was performed to explore the effects of taking bicyclol within one month of receiving anti-TB treatment by analyzing risk factors for liver dysfunction.Results In the multivariable regression analysis of risk factors associated with abnormal liver function,female was less likely to develop liver dysfunction than male(OR:0.69,95%CI:0.51-0.92).The risk of liver dysfunction was lower in participants who took bicyclol within one month after receiving anti-tuberculosis treatment compared to those who did not take(OR:0.38,95%CI:0.28-0.51).Conclusions Taking bicyclol within one month of receiving anti-TB treatment could significantly reduce the occurrence of liver dysfunction.Further research is needed to investigate the potential mechanisms underlying liver function abnormalities in different genders.关键词
结核病/肝功能异常/双环醇/风险分析Key words
Tuberculosis/Liver dysfunction/Bicyclol/Risk analysis引用本文复制引用
孙玙贤,王玉峰,高静韬,杜建,刘宇红,高孟秋..抗结核治疗1个月内服用双环醇的疗效分析[J].中国医学前沿杂志（电子版）,2025,17(7):56-59,4.基金项目
Beijing Municipal Health Commission's High Level Public Health Technical Talent Training Plan(03-11) （03-11）
Beijing Municipal Health Commission's High Level Public Health Technical Talent Training Plan(02-010) 北京市卫生健康委员会高层次公共卫生技术人才建设项目(学科带头人-03-11) （02-010）
北京市卫生健康委员会高层次公共卫生技术人才建设项目(学科带头人-02-010) （学科带头人-02-010）
