中华临床免疫和变态反应杂志2025,Vol.19Issue(4):274-282,9.DOI:10.3969/j.issn.1673-8705.2025.04.011
鼻腔上皮屏障功能障碍在变应性鼻炎发病机制中的作用
Overview of nasal epithelial barrier dysfunction in allergic rhinitis
摘要
Abstract
Allergic rhinitis affects over 20%people in the world.Although there are many treatments to control the symptoms,it's difficult to address problem like clinical recurrence,and the pathogenesis still need further research.Nasal epithelial barrier is the first line of defense of respiratory tract,and its function plays an important role in nasal inflammation.This article summarizes the role of nasal epithelial barrier function in the pathogenesis of allergic rhinitis.关键词
上皮屏障/变应性鼻炎/2型免疫反应Key words
epithelial barrier/allergic rhinitis/type 2 immunity引用本文复制引用
范宇豪,徐苗苗,任丽娅,李静..鼻腔上皮屏障功能障碍在变应性鼻炎发病机制中的作用[J].中华临床免疫和变态反应杂志,2025,19(4):274-282,9.基金项目
国家自然科学基金(81900921) National Natural Science Foundation of China(81900921) (81900921)