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本院2020-2023年胸心外科感染病原菌特点及耐药情况分析

陆俊沛 罗佩

中国医药科学2025,Vol.15Issue(16):127-131,5.
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中国医药科学2025,Vol.15Issue(16):127-131,5.DOI:10.20116/j.issn2095-0616.2025.16.25

本院2020-2023年胸心外科感染病原菌特点及耐药情况分析

Analysis of pathogenic bacteria and drug resistance of thoracic and Department of Cardiothoracic Surgery infection in our hospital from 2020 to 2023

陆俊沛 1罗佩2

作者信息

  • 1. 广西壮族自治区钦州市第一人民医院临床药学科,广西 钦州 535099
  • 2. 广西壮族自治区钦州市第一人民医院胸心外科,广西 钦州 535099
  • 折叠

摘要

Abstract

Objective To understand the characteristics and drug resistance of pathogenic bacteria in thoracic and cardiac surgery in the First People's Hospital of Qinzhou 2020 to 2023,so as to reduce the risk of nosocomial infection.Methods A retrospective analysis was performed on 1242 patients admitted to Department of Cardiothoracic Surgery in the First People's Hospital of Qinzhou from January 2020 to December 2023.The etiological data were collected,and the risk of infection,infection site,pathogen distribution and susceptibility of commonly used antibiotics were analyzed.Results From 2020 to 2023,there were 1242 cases of Department of Cardiothoracic Surgery in the First People's Hospital of Qinzhou,among which 191 cases had postoperative nosocomial infection,the total incidence was 15.38%,and the nosocomial infection rate decreased year by year.Among 191 patients with postoperative infection after thoracic and cardiac surgery,respiratory system infection was the most common,accounting for 58.64%.Among 191 patients with postoperative infection,274 strains of pathogenic bacteria were isolated,including 122 strains of gram-negative bacteria(44.53%),mainly Acinetobacter baumannii(25.55%),140 strains of gram-positive bacteria(51.09%),12 strains of fungi and Candida albicans(4.38%).The resistance rate of Staphylococcus haemolyticus and Staphylococcus aureus to vancomycin was the lowest,both were 0.The resistance rate of Acinetobacter baumannii to cefoperazone/sulbactam was 48.57%.The resistance rate of Pseudomonas aeruginosa to piperacillin/tazobactam and cefoperazone/sulbactam was higher,while resistance rate to cefepime and meropenem are comparatively lower at 21.74%and 32.61%,respectively.Conclusion The incidence of nosocomial infection is high after thoracic and cardiac surgery,so clinical work should focus on strengthening the prevention and management of nosocomial infection.When patients present with symptoms of infection,pathogen culture and susceptibility testing are needed to make effective anti-infective treatment decisions.

关键词

胸心外科/病原菌/药敏试验/医院感染

Key words

Department of Cardiothoracic Surgery/Pathogenic bacteria/Drug susceptible test/Nosocomial infection

分类

医药卫生

引用本文复制引用

陆俊沛,罗佩..本院2020-2023年胸心外科感染病原菌特点及耐药情况分析[J].中国医药科学,2025,15(16):127-131,5.

中国医药科学

2095-0616

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