肿瘤防治研究2025，Vol.52Issue(9)：764-769,6.DOI:10.3971/j.issn.1000-8578.2025.25.0084
钆塞酸二钠3.0T MRI增强对青中年小肝癌MVI的预测价值
Prediction Value of Gd-EOB-DTPA 3.0T Enhanced MRI for MVI of Small Hepat-ocellular Carcinoma in Young and Middle-Aged Patients
刘鹏 1牛美晨 2刘宏3
作者信息
- 1. 236000 阜阳,阜阳市人民医院CT/MR室
- 2. 236000 阜阳,阜阳市第三人民医院十三病区
- 3. 236000 阜阳,阜阳市第五人民医院康复科
- 折叠
摘要
Abstract
Objective To evaluate the predictive value of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(Gd-EOB-DTPA)3.0T enhanced magnetic resonance imaging(MRI)for microvascular invasion(MVI)in young and middle-aged patients with small hepatocellular carcinoma(SHCC).Methods Seventy young and middle-aged patients with SHCC were divided into MVI(n=21)and non-MVI(n=49)groups.All patients underwent preoperative univariate analysis of qualitative and quantitative parameters of Gd-EOB-DTPA MRI enhancement,and multivariate logistic regression was performed using the parameters that differed between groups as independent variables.Receiver operating characteristic and Kaplan-Meier survival curves were drawn to determine the predictive parameters and predict postoperative recurrence and metastasis.Results Significant differences in the qualitative parameters of tumor shape,tumor margin,pseudocapsule completeness,peritumoral hypointensity in the hepatobiliary phase,and peritumoral enhancement in the artery phase were found between the MVI and non-MVI groups(P<0.05);with regard to the quantitative parameters,the apparent diffusion coefficient(ADC)values of tumors between two groups were statistically significant(P<0.05).Multivariate logistic regression analysis showed that small ADC,peritumoral hypointensity in the hepatobiliary phase,and peritumoral enhancement were independent risk factors of MVI in young and middle-aged patients with SHCC(P<0.05).Survival analysis revealed that the recurrence rate of the MVI group was higher than that of the non-MVI group in the first two years.Conclusion Gd-EOB-DTPA-enhanced MRI is valuable in predicting the presence of MVI and postop-erative recurrence and metastasis in young and middle-aged patients with SHCC.关键词
钆塞酸二钠/3.0T磁共振增强/青中年/小肝癌/微血管侵犯Key words
GD-EOB-DTPA/3.0T enhanced magnetic resonance imaging/Young and middle aged/Small hepatocellular carcinoma/Microvascular invasion分类
医药卫生引用本文复制引用
刘鹏,牛美晨,刘宏..钆塞酸二钠3.0T MRI增强对青中年小肝癌MVI的预测价值[J].肿瘤防治研究,2025,52(9):764-769,6.
