肿瘤防治研究2025，Vol.52Issue(9)：776-780,5.DOI:10.3971/j.issn.1000-8578.2025.25.0369
EGCG抗肿瘤作用机制的研究进展
Research Progress on Antitumor Mechanisms of EGCG
摘要
Abstract
Epigallocatechin gallate(EGCG),the most abundant catechin in green tea,possesses various biomedical activities and has garnered significant attention because of its notable anticancer properties.This article reviews the research progress on the antitumor mechanisms of EGCG,focusing on its roles in inducing tumor cell apoptosis;inhibiting tumor cell proliferation,angiogenesis,invasion and metastasis;modulating the tumor microenvironment;and influencing epigenetic modifications.Given its natural origin,safety,and low cost,EGCG could be a preferred option for the development of new cancer therapeutic drugs or enhancing the efficacy of combination therapies.This work aims to provide a theoretical foundation for further research and development of EGCG and scientific evidence for its application in cancer prevention and treatment.关键词
表没食子儿茶素没食子酸酯/抗肿瘤/作用机制Key words
Epigallocatechin gallate/Antitumor/Mechanism分类
医药卫生引用本文复制引用
武安可,李海洋,荣维淇,肖汀,吴健雄..EGCG抗肿瘤作用机制的研究进展[J].肿瘤防治研究,2025,52(9):776-780,5.基金项目
National Key Research and Development Program of China(No.B162302-5) 国家重点研发计划(中医药现代化研究)(B162302-5) （No.B162302-5）
