摘要
Abstract
Objective:To investigate the differences of quantitative parameters of dual-layer spectral detector CT(SDCT)in mediastinal lymph node tuberculosis and mediastinal lymph node metastases of non-small cell lung cancer.Methods:A retrospective analysis was made on 97 lymph nodes from 41 patients with mediastinal lymph node tuberculosis(tuberculosis group)and 108 lymph nodes from 48 patients with mediastinal lymph node metastasis of non-small cell lung cancer(metastatic tumor group)who underwent thoracic SDCT examination and were clinically confirmed.SDCT images were post-processed,and the parameters were measured,including standardised iodine density(nID),standardised effective atomic number(nZeff)and slope of the energy spectrum curve λ40-70 and λ70-100 in the maximal level of the lymph nodes and in the high-density and low-density areas in the plain,arterial,and venous phases.And the differences in the values of each parameter of the two groups were compared.And the diagnostic experiments on indicators with statistically significant differences between the two groups were conducted to evaluate their differential diagnostic value for lymph node tuberculosis and mediastinal lymph node metastasis in lung cancer.Results:During the arterial phase,the nID,nZeff,λ40-70,λ70-100 at the maximal level of lymph nodes,the nID,nZeff and λ 70-100 in the high-density area of lymph nodes,and the nZeff in the low-density area of lymph nodes between the two groups were significantly different(all P<0.05).During the venous phase,the nID,nZeff,λ40-70,λ70-100 in the high-density area of lymph nodes between the two groups were significantly different(all P<0.05),while there were no statistically significant difference in the parameters at the maximal level of lymph nodes or in the low-density area of lymph nodes between the two groups(all P>0.05).Conclusions:The quantitative parameters,nID,nZeff,λ40-70,λ70-100,in the arterial phase and venous phase of SDCT are valuable for the differential diagnosis of mediastinal lymph node tuberculosis and mediastinal lymph node metastasis from non-small-cell lung cancer,whereas the quantitative parameters in the plain phase are difficult to differentiate between the two.关键词
结核,淋巴结/癌,非小细胞肺/淋巴转移/体层摄影术,X线计算机Key words
Tuberculosis,lymph node/Carcinoma,non-small-cell lung/Lymphatic metastasis/Tomography,X-ray computed
